Modular Regiodivergent Synthesis of Benzo-Fused Isocoumarins by a Cyclopropane Aromatization Strategy.
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DOI: 10.1021/acs.orglett.2c02535
Abstract: Reported herein is an electrophile-modulated aromatization reaction of highly functionalized cyclopropanes to structurally diverse benzoisocoumarins featuring concurrent formation of the benzenoid and α-pyrone rings under mild conditions. An aromatization reaction of the proposed benzonorcaradiene intermediates… read more here.
Keywords: aromatization; modular regiodivergent; regiodivergent synthesis; benzo fused ... See more keywords