One-pot synthesis of novel fused pentacyclic chromenopyrimidobenzimidazolones and benzimidazolyl-chromenyl-substituted thiazolidinones
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2016.11.022
Abstract: Abstract The ultrasound promoted synthesis of a number of novel fused pentacyclic chromenopyrimido[1,2- α ]benzimidazolones by the one-pot reaction of 3-formylchromones with 2-aminobenzimidazole is described. Moreover, the isolated pentacyclic chromone derivatives upon microwave irradiation with… read more here.
Keywords: fused pentacyclic; novel fused; synthesis; one pot ... See more keywords
Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy.
Sign Up to like & getrecommendations! Published in 2023 at "Bioorganic chemistry"
DOI: 10.2139/ssrn.4273789
Abstract: Ganoapplins A and B (1 and 2) with a 6/6/6/5/6-fused pentacyclic skeleton containing an aromatic E ring, were obtained from Ganoderma applanatum. Their structures were established through extensive spectroscopic analyses, quantum chemical calculations, including calculated… read more here.
Keywords: inhibit tau; activating autophagy; pentacyclic skeleton; fused pentacyclic ... See more keywords