Targeting Parallel Topology of G-Quadruplex Structures by Indole- Fused Quindoline Scaffolds.
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DOI: 10.1021/acs.biochem.2c00373
Abstract: Preferential stabilization of G-quadruplex (G4) structures using small-molecule ligands has emerged as an effective approach to develop anticancer drugs. Herein, we report the synthesis of three indole-fused quindoline derivatives with varying lengths of side chains… read more here.
Keywords: topology; indole fused; fused quindoline; targeting parallel ... See more keywords