Articles with "fused quinoline" as a keyword



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Facile Route to the Synthesis of 1,3-Diazahetero-Cycle-Fused [1,2-a]Quinoline Derivatives via Cascade Reactions

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Published in 2018 at "ACS Omega"

DOI: 10.1021/acsomega.7b01856

Abstract: A one-step protocol without transition-metal catalysts with simple post-treatment for the synthesis of 1,3-diazaheterocycle-fused [1,2-a]quinoline derivatives via the cascade reaction of 2-fluorobenzaldehyde (1) and heterocyclic ketene aminals (2) was developed. In the one-step cascade reaction,… read more here.

Keywords: via cascade; facile route; fused quinoline; derivatives via ... See more keywords
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Synthesis of Fused Quinoline Derivatives With Antiproliferative Activities and Tyrosine Kinases, Pim-1 Kinase Inhibitions.

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Published in 2022 at "Acta chimica Slovenica"

DOI: 10.17344/acsi.2021.6733

Abstract: Cyclohexan-1,3-dione (1) reacted with either 2-aminoprop-1-ene-1,1,3-tricarbonitrile (2a) or diethyl 3-amino-2-cyanopent-2-enedioate (2b) to give the 5,6,7,8-tetrahydronaphthalene derivatives 3a and 3b, respectively. The latter compounds underwent further heterocyclization reactions to give the thieno[2',3':5,6]benzo[1,2-e][1,3]oxazine derivatives. On the other… read more here.

Keywords: quinoline derivatives; derivatives antiproliferative; tyrosine kinases; synthesis fused ... See more keywords