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Published in 2018 at "ACS Omega"
DOI: 10.1021/acsomega.7b01856
Abstract: A one-step protocol without transition-metal catalysts with simple post-treatment for the synthesis of 1,3-diazaheterocycle-fused [1,2-a]quinoline derivatives via the cascade reaction of 2-fluorobenzaldehyde (1) and heterocyclic ketene aminals (2) was developed. In the one-step cascade reaction,…
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Keywords:
via cascade;
facile route;
fused quinoline;
derivatives via ... See more keywords
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Published in 2022 at "Acta chimica Slovenica"
DOI: 10.17344/acsi.2021.6733
Abstract: Cyclohexan-1,3-dione (1) reacted with either 2-aminoprop-1-ene-1,1,3-tricarbonitrile (2a) or diethyl 3-amino-2-cyanopent-2-enedioate (2b) to give the 5,6,7,8-tetrahydronaphthalene derivatives 3a and 3b, respectively. The latter compounds underwent further heterocyclization reactions to give the thieno[2',3':5,6]benzo[1,2-e][1,3]oxazine derivatives. On the other…
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Keywords:
quinoline derivatives;
derivatives antiproliferative;
tyrosine kinases;
synthesis fused ... See more keywords