Articles with "fused thiophene" as a keyword



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In Vitro Anticancer Activity Screening of Novel Fused Thiophene Derivatives as VEGFR-2/AKT Dual Inhibitors and Apoptosis Inducers

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Published in 2022 at "Pharmaceuticals"

DOI: 10.3390/ph15060700

Abstract: Protein kinases are seen as promising targets in controlling cell proliferation and survival in treating cancer where fused thiophene synthon was utilized in many kinase inhibitors approved by the FDA. Accordingly, this work focused on… read more here.

Keywords: cell; vegfr akt; vitro anticancer; activity ... See more keywords