Twisted diphenoquinones fused with thiophene rings: thiophene analogs of bianthrone.
Sign Up to like & getrecommendations! Published in 2024 at "Chemical communications"
DOI: 10.1039/d4cc02943g
Abstract: The twisted conformer of bistricyclic aromatic enes (BAEs) has a small HOMO-LUMO gap owing to the twisted double bond. In this study, we synthesized diphenoquinones fused with thiophene rings as a new twisted conformer-predominant BAE.… read more here.
Keywords: twisted diphenoquinones; fused thiophene; rings thiophene; diphenoquinones fused ... See more keywords
Sulfinfinitenes: infinitenes of fused thiophene rings.
Sign Up to like & getrecommendations! Published in 2024 at "Chemical communications"
DOI: 10.1039/d4cc05179c
Abstract: Sulfinfinitenes, analogues of infinitene constructed from thiophene rings and assembled by applying a "cut-twist-restitch" sequence to two sulflowers, are explored through DFT calculations. The sulfinfinitene with 16 thiophene rings is only slightly more strained than… read more here.
Keywords: infinitenes fused; sulfinfinitenes infinitenes; fused thiophene; thiophene rings ... See more keywords
In Vitro Anticancer Activity Screening of Novel Fused Thiophene Derivatives as VEGFR-2/AKT Dual Inhibitors and Apoptosis Inducers
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15060700
Abstract: Protein kinases are seen as promising targets in controlling cell proliferation and survival in treating cancer where fused thiophene synthon was utilized in many kinase inhibitors approved by the FDA. Accordingly, this work focused on… read more here.
Keywords: cell; vegfr akt; vitro anticancer; activity ... See more keywords