Intranasal administration of temozolomide combined with focused ultrasound to enhance the survival of mice with glioma (A Pilot Study)
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DOI: 10.1121/1.5035648
Abstract: Intranasal route provides therapeutics direct access to the brain through the nose-to-brain pathway, bypassing the BBB and minimizing systemic exposure. However, nasal delivery is limited by its low delivery efficiency and non-localized delivery. Focused ultrasound-enhanced… read more here.
Keywords: focused ultrasound; delivery; fusin; study ... See more keywords