Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses.
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DOI: 10.1016/j.celrep.2019.09.009
Abstract: BRAF fusions are detected in numerous neoplasms, but their clinical management remains unresolved. We identified six melanoma lines harboring BRAF fusions representative of the clinical cases reported in the literature. Their unexpected heterogeneous responses to… read more here.
Keywords: genetic heterogeneity; braf fusions; braf; fusion kinases ... See more keywords