Molecular investigation of ALK‐rearranged epithelioid fibrous histiocytomas identifies CLTC as a novel fusion partner and evidence of fusion‐independent transcription activation
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.1002/gcc.23038
Abstract: Epithelioid fibrous histiocytoma (EFH) is a rare cutaneous neoplasm, which is characterized by the presence of rearrangements involving the ALK gene. Although EFH was long considered a variant of fibrous histiocytoma, the identification of its… read more here.
Keywords: fusion partner; fusion; epithelioid fibrous; alk ... See more keywords
Secretome-based screening of fusion partners and their application in recombinant protein secretion in Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2021 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-021-11750-9
Abstract: For the efficient production of heterologous proteins in the yeast Saccharomyces cerevisiae, we screened for a novel fusion partner from the yeast secretome. From twenty major proteins identified from the yeast secretome, we selected Scw4p,… read more here.
Keywords: heterologous proteins; fusion partner; fusion; secretion ... See more keywords
BCR: a promiscuous fusion partner in hematopoietic disorders
Sign Up to like & getrecommendations! Published in 2019 at "Oncotarget"
DOI: 10.18632/oncotarget.26837
Abstract: Considerable advances have been made in our understanding of the molecular basis of hematopoietic cancers. The discovery of the BCR-ABL fusion protein over 50 years ago has brought about a new era of therapeutic progress… read more here.
Keywords: bcr; partner hematopoietic; hematopoietic disorders; fusion partner ... See more keywords