Targeting the latent cytomegalovirus reservoir with an antiviral fusion toxin protein
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms14321
Abstract: Reactivation of human cytomegalovirus (HCMV) in transplant recipients can cause life-threatening disease. Consequently, for transplant recipients, killing latently infected cells could have far-reaching clinical benefits. In vivo, myeloid cells and their progenitors are an important… read more here.
Keywords: protein; latently infected; infected cells; fusion toxin ... See more keywords
In silico design of fusion toxin DT389GCSF and comparison of interaction it with GCSF receptor rather than DT486GCSF.
Sign Up to like & getrecommendations! Published in 2018 at "Current computer-aided drug design"
DOI: 10.2174/1573409914666181012151242
Abstract: BACKGROUND The negative effect of chemotherapy and radiotherapy on normal tissues as well as the high expense and length of these treatments have recently attracted researchers to the new methods that specifically affect cancerous tissues… read more here.
Keywords: protein; gcsf; fusion toxin; fusion ... See more keywords