Production of afucosylated antibodies in CHO cells by coexpression of an anti‐FUT8 intrabody
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DOI: 10.1002/bit.28127
Abstract: Some effector functions prompted by immunoglobulin G (IgG) antibodies, such as antibody‐dependent cell‐mediated cytotoxicity (ADCC), strongly depend on the N‐glycans linked to asparagine 297 of the Fc region of the protein. A single α‐(1,6)‐fucosyltransferase (FUT8)… read more here.
Keywords: fut8 intrabody; production; anti fut8; intrabody ... See more keywords