Quantifying the bias in the estimated treatment effect in randomized trials having interim analyses and a rule for early stopping for futility.
Sign Up to like & getrecommendations! Published in 2017 at "Statistics in medicine"
DOI: 10.1002/sim.7242
Abstract: In this paper, we consider the potential bias in the estimated treatment effect obtained from clinical trials, the protocols of which include the possibility of interim analyses and an early termination of the study for… read more here.
Keywords: futility; treatment; interim analyses; bias ... See more keywords
Medical futility regarding cardiopulmonary resuscitation in in-hospital cardiac arrests of adult patients: A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Resuscitation"
DOI: 10.1016/j.resuscitation.2021.11.041
Abstract: AIM For some patients, survival with good neurologic function after cardiopulmonary resuscitation (CPR) is highly unlikely, thus CPR would be considered medically futile. Yet, in clinical practice, there are no well-established criteria, guidelines or measures… read more here.
Keywords: futility; adult patients; hospital; medical futility ... See more keywords
Modelling futility in the setting of fertility treatment.
Sign Up to like & getrecommendations! Published in 2022 at "Human reproduction"
DOI: 10.1093/humrep/deac051
Abstract: When is a fertility treatment futile? This question has great practical importance, given the role futility plays in ethical, legal and clinical discussions. Here, we outline a novel method of determining futility for IVF treatments.… read more here.
Keywords: futility; treatment; ivf treatments; fertility treatment ... See more keywords
Getting The Balance Right: Medical Futility, Scientific Advancement, and the Role of Law.
Sign Up to like & getrecommendations! Published in 2020 at "Medical law review"
DOI: 10.1093/medlaw/fwaa011
Abstract: The concept of medical futility as an applied ethical framework has seen a rise and fall in its popularity over the last 30 years. It is a term used in relation to the assessment of… read more here.
Keywords: futility; law; scientific advancement; medical futility ... See more keywords
Predicting Futility in Severely Injured Patients: Using Arrival Lab Values and Physiology to Support Evidence-Based Resource Stewardship.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American College of Surgeons"
DOI: 10.1097/xcs.0000000000000563
Abstract: BACKGROUND The recent pandemic exposed a largely unrecognized threat to medical resources, including daily available blood products. Some of the most severely injured patients who arrive in extremis consume tremendous resources yet succumb shortly after… read more here.
Keywords: futility; injured patients; severely injured; physiology ... See more keywords
An evolutionary concept analysis of futility in health care
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DOI: 10.1111/jan.13526
Abstract: AIM To report a concept analysis of futility in health care. BACKGROUND Each member of the healthcare team: the physician, the nurse, the patient, the family and all others involved perceive futility differently. The current… read more here.
Keywords: concept; futility; concept analysis; futility health ... See more keywords
24 An audit into the number of patients suffering out-of-hospital cardiac arrest that are resuscitated despite a high likelihood of futility
Sign Up to like & getrecommendations! Published in 2017 at "Emergency Medicine Journal"
DOI: 10.1136/emermed-2017-207308.24
Abstract: Background For a significant number of patients suffering out-of-hospital cardiac arrest (OHCA) cardiopulmonary resuscitation (CPR) is likely to be futile and attempting it may be the wrong thing to do. Anticipatory care plans with do-not-attempt… read more here.
Keywords: risk; futility; high risk; patients suffering ... See more keywords
Association of medical futility with do-not-resuscitate (DNR) code status in hospitalised patients
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Ethics"
DOI: 10.1136/medethics-2020-106977
Abstract: Guidelines recommend a ‘do-not-resuscitate’ (DNR) code status for inpatients in which cardiopulmonary resuscitation (CPR) attempts are considered futile because of low probability of survival with good neurological outcome. We retrospectively assessed the prevalence of DNR… read more here.
Keywords: dnr code; futility; code status; code ... See more keywords
Guideline-defined futility or patient-reported outcomes to assess treatment success after TAVI: what to use? Results from a prospective cohort study with long-term follow-up
Sign Up to like & getrecommendations! Published in 2018 at "Open Heart"
DOI: 10.1136/openhrt-2018-000879
Abstract: Objective Transcatheter aortic valve implantation (TAVI) provides a significant symptom relief and mortality reduction in most patients; however, a substantial group of patients does not experience the same beneficial results according to physician-determined outcomes. Methods… read more here.
Keywords: futility; guideline defined; mortality; tavi ... See more keywords
Futility Disputes: A Review of the Literature and Proposed Model for Dispute Navigation Through Trust Building
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Intensive Care Medicine"
DOI: 10.1177/0885066616666001
Abstract: Futility disputes in the intensive care unit setting have received significant attention in the literature over the past several years. Although the idea of improving communication in an attempt to resolve these challenging situations has… read more here.
Keywords: literature; futility; dispute navigation; trust ... See more keywords
The new futility? The rhetoric and role of “suffering” in pediatric decision-making
Sign Up to like & getrecommendations! Published in 2019 at "Nursing Ethics"
DOI: 10.1177/0969733019840745
Abstract: This article argues that while the presence and influence of “futility” as a concept in medical decision-making has declined over the past decade, medicine is seeing the rise of a new concept with similar features:… read more here.
Keywords: decision; futility; claims patient; patient suffering ... See more keywords