Futility of Up-Front Resection for Anatomically Resectable Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Surgery"
DOI: 10.1001/jamasurg.2024.2485
Abstract: This study attempts to develop a futility risk model using a multi-institutional database and provide unified criteria associated with a futility likelihood below a safety threshold of 20%. read more here.
Keywords: anatomically resectable; futility; front resection; resectable pancreatic ... See more keywords
The Whys, Whens, and Hows of Futility Monitoring
Sign Up to like & getrecommendations! Published in 2025 at "Statistics in Medicine"
DOI: 10.1002/sim.70117
Abstract: There are different reasons to include futility monitoring in clinical trials. We often think of futility monitoring as being planned for business decisions, to limit time and money in a trial that will likely fail… read more here.
Keywords: whys whens; hows futility; futility monitoring; futility ... See more keywords
Quantifying the bias in the estimated treatment effect in randomized trials having interim analyses and a rule for early stopping for futility.
Sign Up to like & getrecommendations! Published in 2017 at "Statistics in medicine"
DOI: 10.1002/sim.7242
Abstract: In this paper, we consider the potential bias in the estimated treatment effect obtained from clinical trials, the protocols of which include the possibility of interim analyses and an early termination of the study for… read more here.
Keywords: futility; treatment; interim analyses; bias ... See more keywords
Medical futility regarding cardiopulmonary resuscitation in in-hospital cardiac arrests of adult patients: A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Resuscitation"
DOI: 10.1016/j.resuscitation.2021.11.041
Abstract: AIM For some patients, survival with good neurologic function after cardiopulmonary resuscitation (CPR) is highly unlikely, thus CPR would be considered medically futile. Yet, in clinical practice, there are no well-established criteria, guidelines or measures… read more here.
Keywords: futility; adult patients; hospital; medical futility ... See more keywords
Modelling futility in the setting of fertility treatment.
Sign Up to like & getrecommendations! Published in 2022 at "Human reproduction"
DOI: 10.1093/humrep/deac051
Abstract: When is a fertility treatment futile? This question has great practical importance, given the role futility plays in ethical, legal and clinical discussions. Here, we outline a novel method of determining futility for IVF treatments.… read more here.
Keywords: futility; treatment; ivf treatments; fertility treatment ... See more keywords
Getting The Balance Right: Medical Futility, Scientific Advancement, and the Role of Law.
Sign Up to like & getrecommendations! Published in 2020 at "Medical law review"
DOI: 10.1093/medlaw/fwaa011
Abstract: The concept of medical futility as an applied ethical framework has seen a rise and fall in its popularity over the last 30 years. It is a term used in relation to the assessment of… read more here.
Keywords: futility; law; scientific advancement; medical futility ... See more keywords
The inability to predict futility in hemorrhaging trauma patients using 4-hour transfusion volumes and rates
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000004541
Abstract: BACKGROUND Blood shortages and utilization stewardship have motivated the trauma community to evaluate futility cutoffs during massive transfusions (MTs). Recent single-center studies have confirmed meaningful survival in ultra-MT (≥20 U) and super-MT (≥50 U), while… read more here.
Keywords: hour; transfusion volumes; futility; mortality ... See more keywords
Predicting Futility in Severely Injured Patients: Using Arrival Lab Values and Physiology to Support Evidence-Based Resource Stewardship.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American College of Surgeons"
DOI: 10.1097/xcs.0000000000000563
Abstract: BACKGROUND The recent pandemic exposed a largely unrecognized threat to medical resources, including daily available blood products. Some of the most severely injured patients who arrive in extremis consume tremendous resources yet succumb shortly after… read more here.
Keywords: futility; injured patients; severely injured; physiology ... See more keywords
An evolutionary concept analysis of futility in health care
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Advanced Nursing"
DOI: 10.1111/jan.13526
Abstract: AIM To report a concept analysis of futility in health care. BACKGROUND Each member of the healthcare team: the physician, the nurse, the patient, the family and all others involved perceive futility differently. The current… read more here.
Keywords: concept; futility; concept analysis; futility health ... See more keywords
24 An audit into the number of patients suffering out-of-hospital cardiac arrest that are resuscitated despite a high likelihood of futility
Sign Up to like & getrecommendations! Published in 2017 at "Emergency Medicine Journal"
DOI: 10.1136/emermed-2017-207308.24
Abstract: Background For a significant number of patients suffering out-of-hospital cardiac arrest (OHCA) cardiopulmonary resuscitation (CPR) is likely to be futile and attempting it may be the wrong thing to do. Anticipatory care plans with do-not-attempt… read more here.
Keywords: risk; futility; high risk; patients suffering ... See more keywords
Association of medical futility with do-not-resuscitate (DNR) code status in hospitalised patients
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Ethics"
DOI: 10.1136/medethics-2020-106977
Abstract: Guidelines recommend a ‘do-not-resuscitate’ (DNR) code status for inpatients in which cardiopulmonary resuscitation (CPR) attempts are considered futile because of low probability of survival with good neurological outcome. We retrospectively assessed the prevalence of DNR… read more here.
Keywords: dnr code; futility; code status; code ... See more keywords