Repurposing Domperidone in Secondary Progressive MS: A Simon 2-Stage Phase 2 Futility Trial
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DOI: 10.1212/wnl.0000000000011863
Abstract: Objective To assess whether treatment with the generic drug domperidone can reduce the progression of disability in secondary progressive multiple sclerosis (SPMS), we conducted a phase 2 futility trial following the Simon two-stage design. Methods… read more here.
Keywords: domperidone; futility; disability; futility trial ... See more keywords