Where is the Future of Drug Discovery for Cancer?
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.01.032
Abstract: With both small molecules and biologics succeeding in trials and in the clinic, the scope of drug discovery in cancer is changing. We asked a group of researchers to share their visions for how to… read more here.
Keywords: drug discovery; discovery cancer; future drug;
Natural compounds as inhibitors of transthyretin amyloidosis and neuroprotective agents: analysis of structural data for future drug design
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2020.1760262
Abstract: Abstract Natural compounds, such as plant and fruit extracts have shown neuroprotective effect against neurodegenerative diseases. It has been reported that several natural compounds binding to transthyretin (TTR) can be useful in amyloidosis prevention. TTR… read more here.
Keywords: natural compounds; ttr; drug design; future drug ... See more keywords
Growing impact of sialic acid-containing glycans in future drug discovery.
Sign Up to like & getrecommendations! Published in 2023 at "Carbohydrate research"
DOI: 10.2139/ssrn.4341534
Abstract: In nature, almost all cells are covered with a complex array of glycan chain namely sialic acids or nuraminic acids, a negatively charged nine carbon sugars which is considered for their great therapeutic importance since… read more here.
Keywords: acid containing; containing glycans; future drug; growing impact ... See more keywords
Future Drug Targets in Periodontal Personalised Medicine—A Narrative Review
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12030371
Abstract: Periodontal disease is an infection-driven inflammatory disease characterized by the destruction of tooth-supporting tissues. The establishment of chronic inflammation will result in progressive destruction of bone and soft tissue changes. Severe periodontitis can lead to… read more here.
Keywords: future drug; drug targets; medicine; targets periodontal ... See more keywords