Sequence-based determinants and prediction of fuzzy interactions in protein complexes.
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DOI: 10.1016/j.jmb.2020.02.017
Abstract: It is becoming increasingly recognized that intrinsically disordered proteins are involved in a wide variety of protein interaction modes. In addition to the well-known process of 'folding upon binding' (disorder-to-order transition), many examples of fuzzy… read more here.
Keywords: fuzzy interactions; disorder; sequence based; based determinants ... See more keywords
Intramolecular Fuzzy Interactions Involving Intrinsically Disordered Domains
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DOI: 10.3389/fmolb.2018.00039
Abstract: Structural disorder is an essential ingredient for function in many proteins and protein complexes. Fuzzy complexes describe the many instances where disorder is maintained as a critical element of protein interactions. In this minireview we… read more here.
Keywords: disordered domains; fuzzy interactions; interactions involving; intramolecular fuzzy ... See more keywords