A novel F8 variant in a Chinese hemophilia A family and involvement of X-chromosome inactivation: A case report
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033665
Abstract: Rationale: Hemophilia A (HA) is an X-linked recessive bleeding disorder, which shows factor VIII (FVIII) deficiency caused by genetic variant in F8 gene. Patient concerns: Males with F8 variants are affected, whereas female carriers with… read more here.
Keywords: chromosome inactivation; chromosome; novel variant; fviii levels ... See more keywords
Determining the Approximate Factor VIII Level Equivalency of Patients with Severe Hemophilia A on Emicizumab Using Global Hemostasis Assays
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-123820
Abstract: Introduction: Patients with severe factor VIII (FVIII) deficiency are defined as having a FVIII level of read more here.
Keywords: predicted fviii; consultancy honoraria; group; consultancy ... See more keywords
Autologous bone marrow-derived MSCs engineered to express oFVIII-FLAG engraft in adult sheep and produce an effective increase in plasma FVIII levels
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1070476
Abstract: Introduction Hemophilia A (HA) is the most common X-linked bleeding disorder, occurring in 1 in 5,000 live male births and affecting >1 million individuals worldwide. Although advances in protein-based HA therapeutics have improved health outcomes,… read more here.
Keywords: plasma fviii; fviii; bone marrow; fviii levels ... See more keywords