A Short Isoform of Coagulation Factor XII mRNA Is Expressed by Neurons in the Human Brain
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2019.05.040
Abstract: Coagulation factor XII (FXII) is synthesized in the liver and secreted into the circulation, where it initiates the contact activation system. Although typically thought to be restricted to the circulation, FXII protein has been found… read more here.
Keywords: isoform; factor xii; coagulation factor; fxii ... See more keywords
Protease Activity in Single-Chain Prekallikrein.
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood.2019002224
Abstract: Prekallikrein (PK) is the precursor of the trypsin-like plasma protease kallikrein (PKa), which cleaves kininogens to release bradykinin and converts the protease precursor factor XII (FXII) to the enzyme FXIIa. PK and FXII undergo reciprocal… read more here.
Keywords: protease; pka; fxii; activity ... See more keywords
Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.1008410
Abstract: Calibrated Automated Thrombography (CAT) is a versatile and sensitive method for analyzing coagulation reactions culminating in thrombin generation (TG). Here, we present a CAT method for analyzing TG in murine whole blood by adapting the… read more here.
Keywords: thrombin generation; coagulation; fxii; mouse whole ... See more keywords