Hepatocyte KLF6 expression affects FXR signalling and the clinical course of primary sclerosing cholangitis
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DOI: 10.1111/liv.14542
Abstract: Primary sclerosing cholangitis (PSC) is characterized by chronic cholestasis and inflammation, which promotes cirrhosis and an increased risk of cholangiocellular carcinoma (CCA). The transcription factor Krueppel‐like‐factor‐6 (KLF6) is a mediator of liver regeneration, steatosis, and… read more here.
Keywords: fxr signalling; klf6 expression; primary sclerosing; klf6 ... See more keywords