VP7 and VP8* genetic characterization of group A rotavirus genotype G12P[8]: Emergence and spreading in the Eastern Brazilian coast in 2014
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DOI: 10.1002/jmv.24605
Abstract: Group A rotavirus (RVA) genotype G12 is habitually associated with diarrhea disease (DD) in African children and recently its detection has increased worldwide. A total of 970 stool samples collected from individuals with DD in… read more here.
Keywords: vp7 vp8; group rotavirus; genotype; g12p ... See more keywords
Complete genome analyses of G12P[8] rotavirus strains from hospitalized children in Surabaya, Indonesia, 2017–2018
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DOI: 10.1002/jmv.28485
Abstract: Rotavirus A (RVA) is a major viral cause of acute gastroenteritis (AGE) worldwide. G12 RVA strains have emerged globally since 2007. There has been no report of the whole genome sequences of G12 RVAs in… read more here.
Keywords: g12; 2017 2018; g12 strains; complete genome ... See more keywords
Phylogeography and evolutionary analysis of African Rotavirus a genotype G12 reveals district genetic diversification within lineage III
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DOI: 10.1016/j.heliyon.2019.e02680
Abstract: Group A rotavirus (RVA) genotype G12 has spread globally and has become one of the most prevalent genotypes of rotavirus in Africa. To understand the drivers for its genetic diversity and rapid spread we investigated… read more here.
Keywords: rotavirus genotype; analysis; genotype g12; rotavirus ... See more keywords
A Single Dose of Anti-HBsAg Antibody-Encoding mRNA-LNPs Suppressed HBsAg Expression: a Potential Cure of Chronic Hepatitis B Virus Infection
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DOI: 10.1128/mbio.01612-22
Abstract: It is the first time that mRNA-LNPs have been used to express anti-HBsAg antibodies (G12-scFv, G12-scFv-Fc, and G12-IgG). G12-scFv-Fc- and G12-IgG-encoding mRNA-LNPs exerted a sustained effect on HBsAg serum clearance in the adeno-associated virus (AAV)/HBV… read more here.
Keywords: g12; hbsag; mrna lnps; scfv g12 ... See more keywords