Abstract 918: Real-world clinical characteristics and treatment (tx) outcomes by co-mutation status in patients (pts) with KRAS G12C-mutated non-small cell lung cancer (NSCLC)
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DOI: 10.1158/1538-7445.am2023-918
Abstract: Background: KRAS mutations occur in ~30% of NSCLC and KRAS G12C is the most common subtype (~40%). Co-mutations can impact NSCLC prognosis and tx response. Methods: This retrospective study used the nationwide (US-based) de-identified Flatiron… read more here.
Keywords: kras g12c; mutation status; status; g12c mutated ... See more keywords
Early-stage KRAS G12C-mutated non-small cell lung cancer (NSCLC) in Australia.
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DOI: 10.1200/jco.2020.38.15_suppl.e21053
Abstract: e21053Background: KRAS is frequently mutated in NSCLC, especially in Caucasian populations. Until recently there have not been effective targeted therapies against KRAS but the recent advent of act... read more here.
Keywords: non small; g12c mutated; stage kras; mutated non ... See more keywords
Response to immunotherapy in KRAS G12C mutated NSCLC: a single-centre retrospective observational study
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DOI: 10.18632/oncotarget.28230
Abstract: Background: Non-small cell lung cancer is the leading cause of cancer death worldwide. New strategies in molecular therapies are being explored to detect and target genetic mutations in NSCLC. Therefore, it is also important to… read more here.
Keywords: kras g12c; immunotherapy kras; response immunotherapy; response ... See more keywords
Morphological and Molecular Characterization of KRAS G12C-Mutated Lung Adenocarcinomas
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DOI: 10.3390/cancers14041030
Abstract: Simple Summary Lung adenocarcinoma is currently the main histological subtype of lung cancer, accounting for more than 60% of diagnosed cases. The most frequent genomic alteration in these tumors is the mutation of the Kirsten… read more here.
Keywords: kras g12c; lung adenocarcinomas; lung; morphological molecular ... See more keywords