An extracellular vesicular mutant KRAS‐associated protein complex promotes lung inflammation and tumor growth
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12307
Abstract: Abstract Extracellular vesicles (EVs) contain more than 100 proteins. Whether there are EVs proteins that act as an ‘organiser’ of protein networks to generate a new or different biological effect from that identified in EV‐producing… read more here.
Keywords: protein complex; inflammation; mutant kras; lung inflammation ... See more keywords
Identification of Dietary Bioflavonoids as Potential Inhibitors against KRAS G12D Mutant—Novel Insights from Computer-Aided Drug Discovery
Sign Up to like & getrecommendations! Published in 2023 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb45030137
Abstract: The KRAS G12D mutation is very frequent in many cancers, such as pancreatic, colon and lung, and has remained undruggable for the past three decades, due to its smooth surface and lack of suitable pockets.… read more here.
Keywords: kras g12d; bioflavonoids potential; dietary bioflavonoids; g12d mutant ... See more keywords