Articles with "g1t38" as a keyword



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Abstract 1522: The CDK4/6 inhibitor G1T38 enhances response to targeted therapies in preclinical models of non-small cell lung cancer

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Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-1522

Abstract: The recent FDA approvals of palbociclib, ribociclib, and abemaciclib in breast cancer validate cyclin-dependent kinases 4 and 6 (CDK4/6) as key therapeutic targets, and warrant investigations in other tumor types with frequently observed alterations in… read more here.

Keywords: cdk4 inhibitor; models non; response; cancer ... See more keywords