TRIM25 enhances cell growth and cell survival by modulating p53 signals via interaction with G3BP2 in prostate cancer
Sign Up to like & getrecommendations! Published in 2018 at "Oncogene"
DOI: 10.1038/s41388-017-0095-x
Abstract: Prostate cancer growth is promoted by the gene regulatory action of androgen receptor (AR) and its downstream signals. The aberrant dysfunction of tumor suppressor p53 has an important role in the prognosis of cancer. We… read more here.
Keywords: prostate cancer; g3bp2; trim25; cancer ... See more keywords
Engagement of the G3BP2-TRIM25 Interaction by Nucleocapsid Protein Suppresses the Type I Interferon Response in SARS-CoV-2-Infected Cells
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DOI: 10.3390/vaccines10122042
Abstract: The nucleocapsid (N) protein contributes to key steps of the SARS-CoV-2 life cycle, including packaging of the virus genome and modulating interactions with cytoplasmic components. Expanding knowledge of the N protein acting on cellular proteins… read more here.
Keywords: nucleocapsid protein; g3bp2; protein; type interferon ... See more keywords
G3BP2, a stress granule assembly factor, is dispensable for spermatogenesis in mice
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DOI: 10.7717/peerj.13532
Abstract: Background Spermatogenesis is a complex process that includes mitosis, meiosis, and spermiogenesis. During spermatogenesis, genetic factors play a vital role inthe formation of properly functioning sperm. GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2) is known… read more here.
Keywords: spermatogenesis; g3bp2; stress granule; dispensable spermatogenesis ... See more keywords