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Supramolecular Polymorphism of (G4C2)n Repeats Associated with ALS and FTD

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22094532

Abstract: Guanine-rich DNA sequences self-assemble into highly stable fourfold structures known as DNA-quadruplexes (or G-quadruplexes). G-quadruplexes have furthermore the tendency to associate into one-dimensional supramolecular aggregates termed G-wires. We studied the formation of G-wires in solutions… read more here.

Keywords: g4c2 formed; g4c2; g4c2 repeats; supramolecular polymorphism ... See more keywords