Ivacaftor Reverses Airway Mucus Abnormalities in a Rat Model Harboring a Humanized G551D-CFTR.
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DOI: 10.1164/rccm.202002-0369oc
Abstract: RATIONALE Animal models have been highly informative for understanding characteristics, onset, and progression of cystic fibrosis (CF) lung disease. In particular, the CFTR-/- rat has revealed insights into the airway mucus defect characteristic of CF,… read more here.
Keywords: airway mucus; rat; g551d; ivacaftor reverses ... See more keywords