Articles with "g6pc mice" as a keyword



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The role of kidney in the inter-organ coordination of endogenous glucose production during fasting

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Published in 2018 at "Molecular Metabolism"

DOI: 10.1016/j.molmet.2018.06.010

Abstract: Objective The respective contributions to endogenous glucose production (EGP) of the liver, kidney and intestine vary during fasting. We previously reported that the deficiency in either hepatic or intestinal gluconeogenesis modulates the repartition of EGP… read more here.

Keywords: g6pc mice; glucose production; mice; gluconeogenesis ... See more keywords
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Yap signalling regulates ductular reactions in mice with CRISPR/Cas9-induced glycogen storage disease type Ia

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Published in 2022 at "Animal Cells and Systems"

DOI: 10.1080/19768354.2022.2139755

Abstract: ABSTRACT Glycogen storage disease type Ia (GSD-Ia) is caused by a deficiency in the glucose-6-phosphatase (G6Pase, G6pc) enzyme, which catalyses the final step of gluconeogenesis and glycogenolysis. Accumulation of G6pc can lead to an increase… read more here.

Keywords: crispr cas9; disease; g6pc mice; yap signalling ... See more keywords