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   Articles with "g6pd" as a keyword



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The CYB5R3c.350C>G and G6PD A alleles modify severity of anemia in malaria and sickle cell disease

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recommendations! Published in 2020 at "American Journal of Hematology"

DOI: 10.1002/ajh.25941

Abstract: Genetic modifiers of anemia in Plasmodium falciparum infection and sickle cell disease (SCD) are not fully known. Both conditions are associated with oxidative stress, hemolysis and anemia. The CYB5R3 gene encodes cytochrome b5 reductase 3,… read more here.

Keywords: g6pd; anemia; cyb5r3c 350c; cell disease ... See more keywords
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Fabricating cholyglycine–glucose‐6‐phosphate dehydrogenase conjugates for cholyglycine detection

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recommendations! Published in 2019 at "Biotechnology and Applied Biochemistry"

DOI: 10.1002/bab.1842

Abstract: To establish cholyglycine (CG) detection via enzyme‐multiplied immunoassay technique (EMIT), glucose‐6‐phosphate dehydrogenase (G6PD) was used as a reporter enzyme to prepare hapten–enzyme conjugate. Gel electrophoresis and UV scanning demonstrated that G6PD was successfully labeled with… read more here.

Keywords: g6pd; cholyglycine detection; phosphate dehydrogenase; glucose phosphate ... See more keywords
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Fabricating cholyglycine-glucose-6-phosphate dehydrogenase conjugates for cholyglycine detection.

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recommendations! Published in 2020 at "Biotechnology and applied biochemistry"

DOI: 10.1002/bab.1983

Abstract: To establish cholyglycine (CG) detection via enzyme multiplied immunoassay technique (EMIT), glucose-6-phosphate dehydrogenase (G6PD) was used as a reporter enzyme to prepare hapten-enzyme conjugate. Gel electrophoresis and UV scanning demonstrated that G6PD was successfully labeled… read more here.

Keywords: g6pd; cholyglycine detection; phosphate dehydrogenase; glucose phosphate ... See more keywords
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Effect of astaxanthin and aluminum chloride on erythrocyte G6PD and 6PGD enzyme activities in vivo and on erythrocyte G6PD in vitro in rats

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recommendations! Published in 2017 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.21954

Abstract: In this study, we investigated the effect of astaxanthin (Ast) and aluminum (Al) on the erythrocyte glucose‐6‐phosphate dehydrogenase (G6PD) and 6‐phosphogluconate dehydrogenase (6PGD) enzymes activities in vivo and on G6PD enzyme in vitro in rats.… read more here.

Keywords: g6pd; enzyme; erythrocyte g6pd; effect astaxanthin ... See more keywords
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Aggressive lymphoma, hemophagocytic lymphohistiocytosis, and G6PD crisis: a lytic cocktail

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recommendations! Published in 2021 at "Annals of Hematology"

DOI: 10.1007/s00277-021-04410-5

Abstract: Dear Editor, We report a case of aggressive lymphoma that received corticosteroids without tumoral lysis prevention and then salvage therapy with rasburicase, inducing glucose-6-phosphate dehydrogenase (G6PD) crisis. A 19-year-old male, originating from Madagascar, was admitted… read more here.

Keywords: aggressive lymphoma; g6pd; rasburicase; g6pd crisis ... See more keywords
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0FF0DTargeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.

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recommendations! Published in 2020 at "Biochemical pharmacology"

DOI: 10.1016/j.bcp.2020.114092

Abstract: Ovarian cancer is one of the leading causes of mortality in women worldwide. Currently, paclitaxel is one of the most effective chemotherapy. While, resistance to paclitaxel is a major cause of therapy failure and the… read more here.

Keywords: g6pd; resistance; ovarian cancer; paclitaxel resistance ... See more keywords

Nicotinamide prevents sweet beverage‐induced hepatic steatosis in rats by regulating the G6PD, NADPH/NADP+ and GSH/GSSG ratios and reducing oxidative and inflammatory stress

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recommendations! Published in 2018 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2017.10.048

Abstract: Abstract The disruption of redox state homeostasis, the overexpression of lipogenic transcription factors and enzymes, and the increase in lipogenic precursors induced by sweetened beverages are determinants of the development of nonalcoholic fatty liver disease.… read more here.

Keywords: g6pd; hepatic steatosis; gsh gssg; steatosis ... See more keywords
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A positive correlation between sickle cell anemia and g6pd deficiency from population of Chhattisgarh, India.

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recommendations! Published in 2019 at "Gene"

DOI: 10.1016/j.gene.2019.04.080

Abstract: OBJECTIVE Present study was undertaken to study the association between sickle cell anemia (SCA) and glucose-6-phosphate dehydrogenase (G6PD) deficiency from Sahu and Kurmi population of Durg and Rajnandgaon district of Chhattisgarh, India. METHOD A random… read more here.

Keywords: g6pd; positive correlation; g6pd deficiency; sickle ... See more keywords
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G6PD diaxBox: Digital image-based quantification of G6PD deficiency.

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recommendations! Published in 2021 at "Talanta"

DOI: 10.1016/j.talanta.2021.122538

Abstract: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy in humans. More than 400 million people worldwide are affected by this genetic condition. Testing for G6PD deficiency before drug administration is essential for patient safety.… read more here.

Keywords: g6pd diaxbox; g6pd; g6pd deficiency; quantification g6pd ... See more keywords
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Disrupting G6PD-mediated Redox homeostasis enhances chemosensitivity in colorectal cancer

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recommendations! Published in 2017 at "Oncogene"

DOI: 10.1038/onc.2017.227

Abstract: Glucose-6-phosphate dehydrogenase (G6PD) is a key enzyme that generates NADPH to maintain reduced glutathione (GSH), which scavenges reactive oxygen species (ROS) to protect cancer cell from oxidative damage. In this study, we mainly investigate the… read more here.

Keywords: g6pd; g6pd mediated; homeostasis enhances; colorectal cancer ... See more keywords
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Genotyping of Malaysian G6PD-deficient neonates by reverse dot blot flow-through hybridisation

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recommendations! Published in 2019 at "Journal of Human Genetics"

DOI: 10.1038/s10038-019-0700-7

Abstract: G6PD deficiency is the commonest enzyme deficiency found in humans. Current diagnostic methods lack sensitivity to detect all cases of G6PD deficiency. We evaluated the reverse dot blot flow-through hybridisation assay designed to detect simultaneously… read more here.

Keywords: blot flow; g6pd; reverse dot; dot blot ... See more keywords