Glucose‐6‐phosphate‐dehydrogenase deficient red blood cell units are associated with decreased posttransfusion red blood cell survival in children with sickle cell disease
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Hematology"
DOI: 10.1002/ajh.25051
Abstract: Chronic transfusion therapy (CTT) for sickle cell disease (SCD) reduces disease morbidity by suppressing the amount of circulating hemoglobin S (HbS)‐containing red blood cells (RBC). The effectiveness of CTT depends on the rate of RBC… read more here.
Keywords: red blood; deficient; deficient units; g6pd deficient ... See more keywords
Brisk clinical response to erythrocytapheresis in a G6PD‐deficient patient with rasburicase‐induced methemoglobinemia
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21540
Abstract: Dear Editor, We read with interest the recent report by Montgomery and Booth, who described a case of methemoglobinemia in a 50-year-old, G6PD-deficient African American man with newly diagnosed T-cell lymphoblastic leukemia being treated with… read more here.
Keywords: range; rasburicase; methemoglobinemia; g6pd deficient ... See more keywords
DNA damage and synaptic and behavioural disorders in glucose-6-phosphate dehydrogenase-deficient mice☆
Sign Up to like & getrecommendations! Published in 2019 at "Redox Biology"
DOI: 10.1016/j.redox.2019.101332
Abstract: Mice deficient in glucose-6-phosphate dehydrogenase (G6PD) cannot replenish the cellular antioxidant glutathione, which detoxifies neurodegenerative reactive oxygen species (ROS). To determine the functional consequences of G6PD deficiency, young and aging G6PD-deficient mice were evaluated for… read more here.
Keywords: dna; deficient; g6pd deficient; mice ... See more keywords
Chloroquine and the potential adverse outcome in undiagnosed G6PD-deficient cases infected with COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Screening"
DOI: 10.1177/0969141320924452
Abstract: Chloroquine (or hydroxychloroquine hereafter referred to as chloroquine), is currently being speculated, amidst growing controversy, as a treatment method for SARSCoV-2 (also known as COVID-19). Exposure to chloroquine for individuals with disorders involving red blood… read more here.
Keywords: g6pd deficiency; g6pd deficient; chloroquine; deficiency ... See more keywords
COVID-19 in G6PD-deficient patients, oxidative stress, and neuropathology.
Sign Up to like & getrecommendations! Published in 2022 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026622666220516111122
Abstract: Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme that regulates energy metabolism mainly through the pentose phosphate pathway (PPP). It is well known that this enzyme participates in the antioxidant/oxidant balance via the synthesis of energy-rich molecules:… read more here.
Keywords: g6pd; g6pd deficient; oxidative stress; covid ... See more keywords
G6pd-Deficient Mice Are Protected From Experimental Cerebral Malaria and Liver Injury by Suppressing Proinflammatory Response in the Early Stage of Plasmodium berghei Infection
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.719189
Abstract: Epidemiological studies provide compelling evidence that glucose-6-phosphate dehydrogenase (G6PD) deficiency individuals are relatively protected against Plasmodium parasite infection. However, the animal model studies on this subject are lacking. Plus, the underlying mechanism in vivo is… read more here.
Keywords: g6pd deficient; mice; liver injury; deficient mice ... See more keywords
Infections in G6PD-Deficient Hospitalized Patients—Prevalence, Risk Factors, and Related Mortality
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DOI: 10.3390/antibiotics11070934
Abstract: G6PD deficiency is a genetic disease that weakens the immune system and renders affected individuals susceptible to infections. In the Sultanate of Oman resides a high number of recorded G6PD cases due to widespread consanguineous… read more here.
Keywords: prevalence; g6pd deficient; infection; risk factors ... See more keywords