Prophylactic Supplementation with Lactobacillus Reuteri or Its Metabolite GABA Protects Against Acute Ischemic Cardiac Injury
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202307233
Abstract: The gut microbiome has emerged as a potential target for the treatment of cardiovascular disease. Ischemia/reperfusion (I/R) after myocardial infarction is a serious complication and whether certain gut bacteria can serve as a treatment option… read more here.
Keywords: acute ischemic; gaba; cardiac injury; reuteri metabolite ... See more keywords
Chromosomal editing of Corynebacterium glutamicum ATCC 13032 to produce gamma‐aminobutyric acid
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2324
Abstract: Corynebacterium glutamicum has been used as a sustainable microbial producer for various bioproducts using cheap biomass resources. In this study, a high GABA‐producing C. glutamicum strain was constructed by chromosomal editing. Lactobacillus brevis‐derived gadB2 was… read more here.
Keywords: corynebacterium glutamicum; atcc 13032; chromosomal editing; glutamicum atcc ... See more keywords
Assessing differential effects of single and accelerated low‐frequency rTMS to the visual cortex on GABA and glutamate concentrations
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Behavior"
DOI: 10.1002/brb3.1845
Abstract: The application of repetitive transcranial magnetic stimulation (rTMS) for therapeutic use in visual‐related disorders and its underlying mechanisms in the visual cortex is under‐investigated. Additionally, there is little examination of rTMS adverse effects particularly with… read more here.
Keywords: assessing differential; rtms; gaba; glutamate ... See more keywords
GABA is an inhibitory neurotransmitter in the neural circuit regulating metamorphosis in a marine snail
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22597
Abstract: The marine mud snail, Tritia (=Ilyanassa) obsoleta, displays a biphasic life cycle. During the initial phase of early development, embryos hatch from benthic egg capsules to become weakly swimming veliger larvae. In the second phase,… read more here.
Keywords: gaba inhibitory; marine; competent larvae; snail ... See more keywords
Microglial VRK2 Regulates Astrocytic GABA Synthesis and Tonic Inhibition in the Thalamus
Sign Up to like & getrecommendations! Published in 2025 at "Glia"
DOI: 10.1002/glia.70101
Abstract: Vaccinia‐related kinase 2 (VRK2) is a prominent genetic risk factor for neurodevelopmental disorders (NDDs), including schizophrenia and epilepsy, which are characterized by cognitive and behavioral impairments. The mediodorsal (MD) thalamus, a higher‐order nucleus involved in… read more here.
Keywords: gaba; microglial vrk2; astrocytic gaba; vrk2 ... See more keywords
The influence of season on glutamate and GABA levels in the healthy human brain investigated by magnetic resonance spectroscopy imaging
Sign Up to like & getrecommendations! Published in 2023 at "Human Brain Mapping"
DOI: 10.1002/hbm.26236
Abstract: Seasonal changes in neurotransmitter systems have been demonstrated in imaging studies and are especially noticeable in diseased states such as seasonal affective disorder (SAD). These modulatory neurotransmitters, such as serotonin, are influencing glutamatergic and GABAergic… read more here.
Keywords: magnetic resonance; glutamate; spectroscopy; brain ... See more keywords
Protective roles of hepatic gamma‐aminobutyric acid signaling in acute ethanol exposure‐induced liver injury
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3544
Abstract: Alcoholic liver disease (ALD) is a consequence of heavy and prolonged alcohol consumptions. We previously demonstrated a hepatic gamma‐aminobutyric acid (GABA) signaling system that protects the liver from toxic injury. The present study was designed… read more here.
Keywords: gamma aminobutyric; gaba; ethanol; acid ... See more keywords
GABA Prevents Sarcopenia by Regulation of Muscle Protein Degradation and Inflammaging in 23‐ to 25‐Month‐Old Female Mice
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13646
Abstract: Sarcopenia is the gradual decrease in skeletal muscle mass, strength and function in elderly individuals. Gamma‐aminobutyric acid (GABA) is a neurotransmitter naturally produced from glutamate by the enzyme glutamic acid decarboxylase. Age‐related decline in GABA… read more here.
Keywords: muscle protein; gaba; muscle; protein degradation ... See more keywords
Maternal glutamine supplementation in murine succinic semialdehyde dehydrogenase deficiency, a disorder of γ‐aminobutyric acid metabolism
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12107
Abstract: Murine succinic semialdehyde dehydrogenase deficiency (SSADHD) manifests with high concentrations of γ‐aminobutyric acid (GABA) and γ‐hydroxybutyrate (GHB) and low glutamine in the brain. To understand the pathogenic contribution of central glutamine deficiency, we exposed aldh5a1−/−… read more here.
Keywords: glutamine supplementation; deficiency; gaba; brain ... See more keywords
GABAergic signaling in human and murine NK cells upon challenge with Toxoplasma gondii
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3hi0720-431r
Abstract: Protective cytotoxic and proinflammatory cytokine responses by NK cells impact the outcome of infections by Toxoplasma gondii, a common parasite in humans and other vertebrates. However, T. gondii can also sequester within NK cells and… read more here.
Keywords: gaba; toxoplasma gondii; human murine; gondii ... See more keywords
Macromolecular‐Suppressed GABA‐Edited MR Spectroscopy in the Posterior Cingulate Cortex of Patients With Acute Mild Traumatic Brain Injury
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28410
Abstract: Mild traumatic brain injury (mTBI) causes a number of molecular and cellular alterations. There is evidence of an imbalance between the main excitatory (glutamate, Glu) and the main inhibitory (gamma‐aminobutyric acid [GABA]) neurotransmitters following mTBI.… read more here.
Keywords: traumatic brain; spectroscopy; mild traumatic; brain injury ... See more keywords