Testosterone is related to GABA+ levels in the posterior-cingulate in unmedicated depressed women during reproductive life.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2018.08.033
Abstract: BACKGROUND The role of testosterone (T) in the pathophysiology of affective disorders and anxiety is broadly supported. Evidence suggests that T has anxiolytic and antidepressant properties. One proposed route for the central effects of T… read more here.
Keywords: depressed women; posterior cingulate; gaba levels; gaba ... See more keywords
The neurochemical basis of the contextual interference effect
Sign Up to like & getrecommendations! Published in 2018 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2018.02.014
Abstract: Efficient practice organization maximizes learning outcome. Although randomization of practice as compared to blocked practice damages training performance, it boosts retention performance, an effect called contextual interference. Motor learning modulates the GABAergic (gamma-aminobutyric acid) system… read more here.
Keywords: contextual interference; gaba levels; practice; effect ... See more keywords
Divergent influences of anterior cingulate cortex GABA concentrations on the emotion circuitry
Sign Up to like & getrecommendations! Published in 2017 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2017.06.055
Abstract: Neuroimaging research has revealed that emotion processing recruits a widespread neural network including the dorsal anterior cingulate cortex (dACC), hippocampus, and amygdala. Recent studies have started to investigate the role of the primary inhibitory neurotransmitter… read more here.
Keywords: emotion circuitry; gaba levels; gaba; cingulate cortex ... See more keywords
Inhibitory and excitatory mechanisms in the human cingulate-cortex support reinforcement learning: A functional Proton Magnetic Resonance Spectroscopy study
Sign Up to like & getrecommendations! Published in 2019 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2018.09.016
Abstract: &NA; The dorsal anterior cingulate cortex (dACC) is crucial for motivation, reward‐ and error‐guided decision‐making, yet its excitatory and inhibitory mechanisms remain poorly explored in humans. In particular, the balance between excitation and inhibition (E/I),… read more here.
Keywords: cognitive load; gaba levels; gaba; cingulate cortex ... See more keywords
Hippocampal GABA levels correlate with retrieval performance in an associative learning paradigm
Sign Up to like & getrecommendations! Published in 2020 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2019.116244
Abstract: Neural plasticity is a complex process dependent on neurochemical underpinnings. Next to the glutamatergic system which contributes to memory formation via long-term potentiation (LTP) and long-term depression (LTD), the main inhibitory neurotransmitter, GABA is crucially… read more here.
Keywords: hippocampal gaba; gaba levels; learning paradigm; gaba ... See more keywords
Task-related measures of short-interval intracortical inhibition and GABA levels in healthy young and older adults: A multimodal TMS-MRS study
Sign Up to like & getrecommendations! Published in 2020 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2019.116470
Abstract: Establishing the associations between magnetic resonance spectroscopy (MRS)-assessed gamma-aminobutyric acid (GABA) levels and transcranial magnetic stimulation (TMS)-derived 'task-related' modulations in GABAA receptor-mediated inhibition and how these associations change with advancing age is a topic of… read more here.
Keywords: task; inhibition; task related; gaba levels ... See more keywords
GABA levels are differentially associated with bimanual motor performance in older as compared to young adults
Sign Up to like & getrecommendations! Published in 2021 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2021.117871
Abstract: Although gamma aminobutyric acid (GABA) is of particular importance for efficient motor functioning, very little is known about the relationship between regional GABA levels and motor performance. Some studies suggest this relation to be subject… read more here.
Keywords: gaba levels; older adults; motor; motor performance ... See more keywords
Posterior Insular GABA Levels Inversely Correlate with the Intensity of Experimental Mechanical Pain in Healthy Subjects
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.09.043
Abstract: This study aimed to investigate the relation of GABA and glutamate levels in the posterior insula and mechanical pain sensitivity in healthy subjects. Nineteen healthy female individuals underwent single voxel magnetic resonance spectroscopy (MRS) at… read more here.
Keywords: posterior insula; mechanical pain; gaba levels; healthy subjects ... See more keywords
The role of MRS-assessed GABA in human behavioral performance
Sign Up to like & getrecommendations! Published in 2022 at "Progress in Neurobiology"
DOI: 10.1016/j.pneurobio.2022.102247
Abstract: Understanding the neurophysiological mechanisms that drive human behavior has been a long-standing focus of cognitive neuroscience. One well-known neuro-metabolite involved in the creation of optimal behavioral repertoires is GABA, the main inhibitory neurochemical in the… read more here.
Keywords: behavioral performance; mrs assessed; gaba levels; performance ... See more keywords
Macromolecule suppressed GABA levels show no relationship with age in a pediatric sample
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-80530-8
Abstract: The inhibitory neurotransmitter γ-Aminobutyric acid (GABA) plays a crucial role in cortical development. Therefore, characterizing changes in GABA levels during development has important implications for the study of healthy development and developmental disorders. Brain GABA… read more here.
Keywords: macromolecule suppressed; age; gaba levels; gaba ... See more keywords
M73. Neuromagnetic 40 Hz Auditory Steady State Responses and Auditory Cortical GABA-Levels in Participants at Ultra-High Risk of Psychosis.
Sign Up to like & getrecommendations! Published in 2017 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbx022.068
Abstract: Abstract Background: The 40 Hz auditory steady state response (ASSR) is robustly impaired in chronic schizophrenia which could reflect impaired GABAergic neurotransmission in auditory cortex. However, little is known about the presence of alterations in… read more here.
Keywords: risk; auditory; gyrus; gaba levels ... See more keywords