Presynaptic nigral GPR55 receptors stimulate [3H]‐GABA release through [3H]‐cAMP production and PKA activation and promote motor behavior
Sign Up to like & getrecommendations! Published in 2022 at "Synapse"
DOI: 10.1002/syn.22246
Abstract: Striatal medium‐sized spiny neurons express mRNA and protein of GPR55 receptors that stimulate neurotransmitter release; thus, GPR55 could be sent to nigral striatal projections, where it might modulate GABA release and motor behavior. Here, we… read more here.
Keywords: gaba release; receptors stimulate; gpr55; gpr55 receptors ... See more keywords
Leptin alters somatosensory thalamic networks by decreasing gaba release from reticular thalamic nucleus and action potential frequency at ventrobasal neurons
Sign Up to like & getrecommendations! Published in 2018 at "Brain Structure and Function"
DOI: 10.1007/s00429-018-1645-x
Abstract: Leptin is an adipose-derived hormone that controls appetite and energy expenditure. Leptin receptors are expressed on extra-hypothalamic ventrobasal (VB) and reticular thalamic (RTN) nuclei from embryonic stages. Here, we studied the effects of pressure-puff, local… read more here.
Keywords: gaba release; ventrobasal; leptin; reticular thalamic ... See more keywords
Fentanyl and naloxone effects on glutamate and GABA release rates from anterior hypothalamus in freely moving rats.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2018.07.029
Abstract: Fentanyl, a μ-opioid receptor agonist, has been studied for its neuro/psycho-pharmacological effects since its first clinical use; however, its effect on the release rate of the Central Nervous System (CNS) neurotransmitters has not been yet… read more here.
Keywords: gaba release; release rates; anterior hypothalamus; glutamate gaba ... See more keywords
NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-25956-y
Abstract: NG2 glia, also known as oligodendrocyte precursor cells (OPCs), play an important role in proliferation and give rise to myelinating oligodendrocytes during early brain development. In contrast to other glial cell types, the most intriguing… read more here.
Keywords: gaba release; ng2 glia; derived gaba; glia derived ... See more keywords
Synapsin I Synchronizes GABA Release in Distinct Interneuron Subpopulations.
Sign Up to like & getrecommendations! Published in 2019 at "Cerebral cortex"
DOI: 10.1093/cercor/bhz174
Abstract: Neurotransmitters can be released either synchronously or asynchronously with respect to action potential timing. Synapsins (Syns) are a family of synaptic vesicle (SV) phosphoproteins that assist gamma-aminobutyric acid (GABA) release and allow a physiological excitation/inhibition… read more here.
Keywords: gaba release; synapsin synchronizes; interneuron subpopulations; release ... See more keywords
VPAC1 and VPAC2 receptor activation on GABA release from hippocampal nerve terminals involve several different signalling pathways
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14051
Abstract: Vasoactive intestinal peptide (VIP) is an important modulator of hippocampal synaptic transmission that influences both GABAergic synaptic transmission and glutamatergic cell excitability through activation of VPAC1 and VPAC2 receptors. Presynaptic enhancement of GABA release contributes… read more here.
Keywords: gaba release; vpac1 vpac2; activation; synaptic transmission ... See more keywords
Syntaxin 1B regulates synaptic GABA release and extracellular GABA concentration, and is associated with temperature‐dependent seizures
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.15159
Abstract: De novo heterozygous mutations in the STX1B gene, encoding syntaxin 1B, cause a familial, fever‐associated epilepsy syndrome. Syntaxin 1B is an essential component of the pre‐synaptic neurotransmitter release machinery as a soluble N‐ethylmaleimide‐sensitive factor attachment… read more here.
Keywords: gaba release; temperature dependent; gaba; release ... See more keywords
Prostaglandin E2 depresses GABA release onto parvocellular neuroendocrine neurones in the paraventricular nucleus of the hypothalamus via presynaptic receptors
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroendocrinology"
DOI: 10.1111/jne.12638
Abstract: Inflammation‐induced activation of the hypothalamic‐pituitary‐adrenal (HPA) axis and the ensuing release of anti‐inflammatory glucocorticoids are critical for the fine‐tuning of the inflammatory response. This immune‐induced neuroendocrine response is in large part mediated by prostaglandin E2… read more here.
Keywords: gaba release; release onto; parvocellular neuroendocrine; depresses gaba ... See more keywords
Interferon-γ augments GABA release in the developing neocortex via nitric oxide synthase/soluble guanylate cyclase and constrains network activity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.913299
Abstract: Interferon-γ (IFN-γ), a cytokine with neuromodulatory properties, has been shown to enhance inhibitory transmission. Because early inhibitory neurotransmission sculpts functional neuronal circuits, its developmental alteration may have grave consequences. Here, we investigated the acute effects… read more here.
Keywords: guanylate cyclase; gaba release; nitric oxide; oxide synthase ... See more keywords
Sex Differences in the Role of Neurexin 3α in Zoster Associated Pain
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Integrative Neuroscience"
DOI: 10.3389/fnint.2022.915797
Abstract: Varicella zoster virus (VZV) induces orofacial pain and female rats show greater pain than male rats. During the proestrus phase of the estrous cycle the VZV induce pain response is attenuated in female rats. A… read more here.
Keywords: female rats; gaba release; central amygdala; proestrus female ... See more keywords
GABA, but Not Bestrophin-1, Is Localized in Astroglial Processes in the Mouse Hippocampus and the Cerebellum
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2020.00135
Abstract: GABA is proposed to act as a gliotransmitter in the brain. Differences in GABA release from astroglia are thought to underlie differences in tonic inhibition between the cerebellum and the CA1 hippocampus. Here we used… read more here.
Keywords: gaba release; hippocampus; hippocampus cerebellum; cerebellum ... See more keywords