RIIβ‐PKA in GABAergic Neurons of Dorsal Median Hypothalamus Governs White Adipose Browning
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202205173
Abstract: The RIIβ subunit of cAMP‐dependent protein kinase A (PKA) is expressed in the brain and adipose tissue. RIIβ‐knockout mice show leanness and increased UCP1 in brown adipose tissue. The authors have previously reported that RIIβ… read more here.
Keywords: dmh gabaergic; wat browning; gabaergic neurons; pka ... See more keywords
Estrogen receptors observed at extranuclear neuronal sites and in glia in the nucleus accumbens core and shell of the female rat: Evidence for localization to catecholaminergic and GABAergic neurons
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25320
Abstract: Estrogens affect dopamine‐dependent diseases/behavior and have rapid effects on dopamine release and receptor availability in the nucleus accumbens (NAc). Low levels of nuclear estrogen receptor (ER) α and ERβ are seen in the NAc, which… read more here.
Keywords: localization; gper1; gabaergic neurons; core shell ... See more keywords
Bulbar projecting subcortical GABAergic neurons send collateral branches extensively and selectively to primary olfactory cortical regions
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25434
Abstract: Circuit operations of the olfactory bulb are modulated by higher order projections from multiple regions, many of which are themselves targets of bulbar output. Multiple glutamatergic regions project to the olfactory bulb, including the anterior… read more here.
Keywords: primary olfactory; olfactory bulb; gabaergic neurons; cortical regions ... See more keywords
Tal2 is required for generation of GABAergic neurons in the zebrafish midbrain
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.534
Abstract: In the zebrafish midbrain, GABAergic neurons develop from precursors located in the nucleus of the medial longitudinal fasciculus (nMLF). However, the precise mechanisms that underline generation of the nMLF GABAergic neuron are poorly understood. read more here.
Keywords: gabaergic neurons; zebrafish midbrain; tal2 required; generation gabaergic ... See more keywords
GABAergic neurons maturation is regulated by a delicate network
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10242
Abstract: Gamma‐aminobutyric acid‐expressing (GABAergic) neurons are implicated in a variety of neuropsychiatric disorders, such as epilepsy, anxiety, autism, and other pathological processes, including cerebral ischemia injury and drug addiction. Therefore, GABAergic neuronal processes warrant further research.… read more here.
Keywords: maturation regulated; maturation; neurons maturation; gabaergic neurons ... See more keywords
Transcriptomic profile of the subiculum-projecting VIP GABAergic neurons in the mouse CA1 hippocampus
Sign Up to like & getrecommendations! Published in 2019 at "Brain Structure and Function"
DOI: 10.1007/s00429-019-01883-z
Abstract: In cortical circuits, the vasoactive intestinal peptide (VIP+)-expressing GABAergic cells represent a heterogeneous but unique group of interneurons that is mainly specialized in network disinhibition. While the physiological properties and connectivity patterns have been elucidated… read more here.
Keywords: projecting vip; vip; subiculum projecting; cell ... See more keywords
Serine Racemase Expression by Striatal Neurons
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-020-00880-9
Abstract: d -serine is synthesized by serine racemase (SR) and is a co-agonist at forebrain N -methyl- d -aspartate receptors (NMDARs). d -serine and SR are expressed primarily in neurons, but not in quiescent astrocytes. In… read more here.
Keywords: serine racemase; serine; expression; mice ... See more keywords
Systemic metabolic benefits of 17α-estradiol are not exclusively mediated by ERα in glutamatergic or GABAergic neurons
Sign Up to like & getrecommendations! Published in 2024 at "GeroScience"
DOI: 10.1007/s11357-024-01192-2
Abstract: 17α-Estradiol (17αE2), a less-feminising enantiomer of 17β-estradiol, has been shown to prolong lifespan and improve metabolic health in a sex-specific manner in male, but not in female mice. Recent studies have demonstrated the pivotal role… read more here.
Keywords: glutamatergic gabaergic; metabolic benefits; systemic metabolic; benefits estradiol ... See more keywords
Aneuploidy is Linked to Neurological Phenotypes Through Oxidative Stress
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-024-02227-1
Abstract: Aneuploidy, having an aberrant genome, is gaining increasing attention in neurodegenerative diseases. It gives rise to proteotoxic stress as well as a stereotypical oxidative shift which makes these cells sensitive to internal and environmental stresses.… read more here.
Keywords: seizure phenotype; oxidative stress; stress; aneuploidy ... See more keywords
Electroacupuncture Alleviates Hyperalgesia and Anxiety-Like Behaviors in Pain Memory Model Rats Through Activation of GABAergic Neurons and GABA Receptor in the Rostral Anterior Cingulate Cortex
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Neurobiology"
DOI: 10.1007/s12035-024-03986-z
Abstract: Recent studies have confirmed that pain memory is often accompanied by negative emotions. Electroacupuncture (EA) can block the retrieval of painful memories, thereby alleviating the associated negative behaviors. However, the underlying mechanism is poorly understood.… read more here.
Keywords: anxiety like; like behaviors; memory; pain memory ... See more keywords
Histamine Excites Rat GABAergic Ventral Pallidum Neurons via Co-activation of H1 and H2 Receptors
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Bulletin"
DOI: 10.1007/s12264-018-0277-8
Abstract: The ventral pallidum (VP) is a crucial component of the limbic loop of the basal ganglia and participates in the regulation of reward, motivation, and emotion. Although the VP receives afferent inputs from the central… read more here.
Keywords: histaminergic system; central histaminergic; histamine excites; ventral pallidum ... See more keywords