Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-00325-2
Abstract: The amyloid precursor protein (APP) modulates synaptic activity, resulting from the fine tuning of excitatory and inhibitory neurotransmission. GABAergic inhibitory neurotransmission is affected by modifications in intracellular chloride concentrations regulated by Na+-K+-2Cl− cotransporter 1 (NKCC1)… read more here.
Keywords: regulation gabaergic; app; gabaergic neurotransmission; expression ... See more keywords
Cellular and molecular signatures of in vivo imaging measures of GABAergic neurotransmission in the human brain.
Sign Up to like & getrecommendations! Published in 2022 at "Communications biology"
DOI: 10.1038/s42003-022-03268-1
Abstract: Diverse GABAergic interneuron networks orchestrate information processing in the brain. Understanding the principles underlying the organisation of this system in the human brain, and whether these principles are reflected by available non-invasive in vivo neuroimaging… read more here.
Keywords: gabaa receptor; gabaergic neurotransmission; human brain; interneuron ... See more keywords
Alpha-linolenic acid enhances the facilitation of GABAergic neurotransmission in the BLA and CA1.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental biology and medicine"
DOI: 10.1177/15353702231165010
Abstract: Hyperexcitability is a major mechanism implicated in several neuropsychiatric disorders, such as organophosphate-induced status epilepticus (SE), primary epilepsy, stroke, spinal cord injury, traumatic brain injury, schizophrenia, and autism spectrum disorders. Underlying mechanisms are diverse, but… read more here.
Keywords: gabaergic neurotransmission; brain; bla; bla ca1 ... See more keywords
Crosstalk Between GABAergic Neurotransmission and Inflammatory Cascades in the Post-ischemic Brain: Relevance for Stroke Recovery
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.807911
Abstract: Adaptive plasticity processes are required involving neurons as well as non-neuronal cells to recover lost brain functions after an ischemic stroke. Recent studies show that gamma-Aminobutyric acid (GABA) has profound effects on glial and immune… read more here.
Keywords: gabaergic neurotransmission; post ischemic; brain; inflammatory cascades ... See more keywords