Neuroligin‐2 controls the establishment of fast GABAergic transmission in adult‐born granule cells
Sign Up to like & getrecommendations! Published in 2023 at "Hippocampus"
DOI: 10.1002/hipo.23505
Abstract: GABAergic inhibition is critical for the precision of neuronal spiking and the homeostatic regulation of network activity in the brain. Adult neurogenesis challenges network homeostasis because new granule cells (GCs) integrate continuously in the functional… read more here.
Keywords: fast gabaergic; adult; adult born; granule cells ... See more keywords
mPFC GABAergic transmission mediated the role of BDNF signaling in cognitive impairment but not anxiety induced by adolescent social stress
Sign Up to like & getrecommendations! Published in 2021 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2020.108412
Abstract: Depression with comorbid anxiety or cognitive symptoms can vary in terms of symptoms, pathophysiology and antidepressant efficacy, but the underlying neurobiological mechanisms remain to be elucidated. Previous studies from our group and others have shown… read more here.
Keywords: mpfc; transmission; anxiety; gabaergic transmission ... See more keywords
Upregulated NMDAR-mediated GABAergic transmission underlies autistic-like deficits in Htr3a knockout mice
Sign Up to like & getrecommendations! Published in 2021 at "Theranostics"
DOI: 10.7150/thno.60531
Abstract: Mutations in serotonin pathway genes, especially the serotonergic receptor subunit gene HTR3A, are associated with autism. However, the association of HTR3A deficiency with autism and the underlying mechanisms remain unknown. Methods: The Htr3a knockout (KO)… read more here.
Keywords: autistic like; autism; gabaergic transmission; htr3a knockout ... See more keywords