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PGC-1α Signaling Increases GABA(A) Receptor Subunit α2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice

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Published in 2021 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2021.588230

Abstract: Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a master regulator of mitochondria biogenesis and cell stress playing a role in metabolic and degenerative diseases. In the brain PGC-1α expression has been localized mainly to GABAergic interneurons… read more here.

Keywords: receptor subunit; anxiety like; expression; pgc ... See more keywords