Gabra5 plays a sexually dimorphic role in POMC neuron activity and glucose balance
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.889122
Abstract: Pro-opiomelanocortin (POMC) neurons are important for the regulation of body weight and glucose balance. The inhibitory tone to POMC neurons is mediated primarily by the GABA receptors. However, the detailed mechanisms and functions of GABA… read more here.
Keywords: gabra5; pomc neurons; glucose balance; pomc ... See more keywords
Ablation of Gabra5 Influences Corticosterone Levels and Anxiety-like Behavior in Mice
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DOI: 10.3390/genes14020285
Abstract: Stress responses are activated by the hypothalamic-pituitary-adrenal axis (HPA axis), culminating in the release of glucocorticoids. During prolonged periods of secretion of glucocorticoids or inappropriate behavioral responses to a stressor, pathologic conditions may occur. Increased… read more here.
Keywords: ablation gabra5; gabra5; gabra5 influences; corticosterone ... See more keywords