Abstract 277: NUC-7738 promotes alternative polyadenylation site usage and reduces glutaminase GAC isoform
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DOI: 10.1158/1538-7445.am2023-277
Abstract: Background: Metabolic dysregulation, a hallmark of cancer, allows tumor cells to sustain high rates of growth and proliferation in unfavorable conditions, including hypoxia. Many cancers, including clear cell renal cell carcinoma (ccRCC), demonstrate the Warburg… read more here.
Keywords: alternative polyadenylation; nuc 7738; polyadenylation; gac isoform ... See more keywords