MR and fluorescence imaging of gadobutrol‐induced optical clearing of red fluorescent protein signal in an in vivo cancer model
Sign Up to like & getrecommendations! Published in 2022 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4708
Abstract: Multimodality registration of optical and MR images in the same tissue volume in vivo may be enabled by MR contrast agents with an optical clearing (OC) effect. The goals of this study were to (a)… read more here.
Keywords: red fluorescent; vivo; gadobutrol; tumor ... See more keywords
Absence of T1 Hyperintensity in the Brain of High-risk Patients After Multiple Administrations of High-dose Gadobutrol for Cardiac Magnetic Resonance
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Neuroradiology"
DOI: 10.1007/s00062-020-00897-z
Abstract: A prospective study was conducted to evaluate signal changes in the dentate nucleus, globus pallidus, pons, and thalamus (normalized to the deep cerebellum white matter) in T1-weighted magnetic resonance (MR) images after serial injections of… read more here.
Keywords: administrations high; gadobutrol; high dose; high risk ... See more keywords
Gadobutrol: A Review in Contrast-Enhanced MRI and MRA
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Drug Investigation"
DOI: 10.1007/s40261-018-0674-9
Abstract: Intravenous gadobutrol [Gadovist™ (EU); Gadavist® (USA)] is a second-generation, extracellular non-ionic macrocyclic gadolinium-based contrast agent (GBCA) that is approved for use in paediatric (including term neonates) and adult patients undergoing diagnostic contrast-enhanced (CE) MRI for… read more here.
Keywords: contrast; gadobutrol; enhanced mri; contrast enhanced ... See more keywords
Genotoxic effects of gadobutrol and gadoversetamide active substances used in magnetic resonance imaging in human peripheral lymphocytes in vitro.
Sign Up to like & getrecommendations! Published in 2022 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2021.1957913
Abstract: Gadobutrol and gadoversetamide are gadolinium-based contrast agents (GBCAs) widely used during magnetic resonance imaging examination. In this study, the genotoxicity of two GBCAs, gadobutrol and gadoversetamide, was investigated by using different endpoints: chromosome aberration (CAs),… read more here.
Keywords: gadobutrol; resonance imaging; magnetic resonance; human peripheral ... See more keywords
Comparison of Unenhanced T1-Weighted Signal Intensities Within the Dentate Nucleus and the Globus Pallidus After Serial Applications of Gadopentetate Dimeglumine Versus Gadobutrol in a Pediatric Population
Sign Up to like & getrecommendations! Published in 2018 at "Investigative Radiology"
DOI: 10.1097/rli.0000000000000419
Abstract: Objective The aim of this study was to evaluate and compare changes in T1-weighted signal intensity (SI) within the dentate nucleus (DN) and globus pallidus (GP) in a pediatric population after serial applications of the… read more here.
Keywords: serial applications; gadopentetate dimeglumine; contrast; gadobutrol ... See more keywords
Different Impact of Gadopentetate and Gadobutrol on Inflammation-Promoted Retention and Toxicity of Gadolinium Within the Mouse Brain
Sign Up to like & getrecommendations! Published in 2022 at "Investigative Radiology"
DOI: 10.1097/rli.0000000000000884
Abstract: Objectives Using a murine model of multiple sclerosis, we previously showed that repeated administration of gadopentetate dimeglumine led to retention of gadolinium (Gd) within cerebellar structures and that this process was enhanced with inflammation. This… read more here.
Keywords: inflammation; retention; gadobutrol; brain ... See more keywords
Efficacy and Safety of Gadopiclenol for Contrast-Enhanced MRI of the Central Nervous System
Sign Up to like & getrecommendations! Published in 2022 at "Investigative Radiology"
DOI: 10.1097/rli.0000000000000944
Abstract: Objectives Developing new high relaxivity gadolinium-based contrast agents (GBCAs) for magnetic resonance imaging (MRI) allowing dose reduction while maintaining similar diagnostic efficacy is needed, especially in the context of gadolinium retention in tissues. This study… read more here.
Keywords: mmol; contrast; gadobutrol; gadopiclenol ... See more keywords
Contrast-to-Dose Relationship of Gadopiclenol, an MRI Macrocyclic Gadolinium-based Contrast Agent, Compared with Gadoterate, Gadobenate, and Gadobutrol in a Rat Brain Tumor Model.
Sign Up to like & getrecommendations! Published in 2019 at "Radiology"
DOI: 10.1148/radiol.2019182953
Abstract: Background Detection of cerebral lesions at MRI may benefit from a chemically stable and more sensitively detected gadolinium-based contrast agent (GBCA). Gadopiclenol, a macrocyclic GBCA with at least twofold higher relaxivity, is currently undergoing clinical… read more here.
Keywords: gadobenate; gadobutrol; contrast; gadopiclenol ... See more keywords
Prospective Safety Study of Intrathecal Gadobutrol in Different Doses
Sign Up to like & getrecommendations! Published in 2023 at "American Journal of Neuroradiology"
DOI: 10.3174/ajnr.a7841
Abstract: The present study adds to the accumulating evidence that intrathecal gadobutrol in doses up to 0.50 mmol is safe. BACKGROUND AND PURPOSE: In our clinical practice, we increasingly use intrathecal contrast-enhanced glymphatic MR imaging to… read more here.
Keywords: gadobutrol; prospective safety; intrathecal gadobutrol; safety study ... See more keywords