Comprehensive Speciation Analysis of Residual Gadolinium in Deep Cerebellar Nuclei in Rats Repeatedly Administered With Gadoterate Meglumine or Gadodiamide
Sign Up to like & getrecommendations! Published in 2022 at "Investigative Radiology"
DOI: 10.1097/rli.0000000000000846
Abstract: Purpose Several preclinical studies have reported the presence of gadolinium (Gd) in different chemical forms in the brain, depending on the class (macrocyclic versus linear) of Gd-based contrast agent (GBCA) administered. The aim of this… read more here.
Keywords: gadodiamide; cerebellar nuclei; comprehensive speciation; spectroscopy ... See more keywords
Long-term effects of linear versus macrocyclic GBCAs on gene expression in the central nervous system of mice
Sign Up to like & getrecommendations! Published in 2025 at "European Radiology Experimental"
DOI: 10.1186/s41747-024-00546-x
Abstract: We examined chronic gadolinium retention impact on gene expression in the mouse central nervous system (CNS) after injection of linear or macrocyclic gadolinium-based contrast agents (GBCAs). From 05/2022 to 07/2023, 36 female mice underwent weekly… read more here.
Keywords: central nervous; nervous system; gene expression; gadolinium ... See more keywords