Evaluation of Gadopiclenol and P846, 2 High-Relaxivity Macrocyclic Magnetic Resonance Contrast Agents Without Protein Binding, in a Rodent Model of Hepatic Metastases: Potential Solutions for Improved Enhancement at Ultrahigh Field Strength.
Sign Up to like & getrecommendations! Published in 2019 at "Investigative Radiology"
DOI: 10.1097/rli.0000000000000572
Abstract: PURPOSE The aim of this study was to evaluate in vitro and in vivo the enhancement properties of experimental gadolinium (Gd)-based contrast agents (GBCAs) with different molecular weights and hydration numbers (P846 and gadopiclenol) compared… read more here.
Keywords: p846; gadoterate; gadopiclenol; gadopentetate ... See more keywords
Different Impact of Gadopentetate and Gadobutrol on Inflammation-Promoted Retention and Toxicity of Gadolinium Within the Mouse Brain
Sign Up to like & getrecommendations! Published in 2022 at "Investigative Radiology"
DOI: 10.1097/rli.0000000000000884
Abstract: Objectives Using a murine model of multiple sclerosis, we previously showed that repeated administration of gadopentetate dimeglumine led to retention of gadolinium (Gd) within cerebellar structures and that this process was enhanced with inflammation. This… read more here.
Keywords: inflammation; retention; gadobutrol; brain ... See more keywords