Enhanced Cellular Transduction of Nanoparticles Resistant to Rapidly Forming Plasma Protein Coronas
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DOI: 10.1002/adbi.202000162
Abstract: Nanoparticles (NPs) are increasingly being developed as biomedical platforms for drug/nucleic acid delivery and imaging. However, in biological fluids, NPs interact with a wide range of proteins that form a coating known as protein corona.… read more here.
Keywords: plasma; gag binding; enhanced cellular; cellular transduction ... See more keywords
The Role of Heparan Sulfate in CCL26-Induced Eosinophil Chemotaxis
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DOI: 10.3390/ijms23126519
Abstract: Proinflammatory chemokine ligand 26 (CCL26, eotaxin-3) mediates transendothelial cell migration of eosinophils by binding and activating the G-protein-coupled (GPC) chemokine receptor 3 on the surface of eosinophilic cells. Here we have investigated the role of… read more here.
Keywords: ccl26 induced; heparan sulfate; eosinophil chemotaxis; ccl26 ... See more keywords
The GAG-Binding Peptide MIG30 Protects against Liver Ischemia-Reperfusion in Mice
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DOI: 10.3390/ijms23179715
Abstract: Ischemia-reperfusion injury (IRI) drives graft rejection and is the main cause of mortality after liver transplantation. During IRI, an intense inflammatory response marked by chemokine production and neutrophil recruitment occurs. However, few strategies are available… read more here.
Keywords: binding peptide; iri; mig30; ischemia reperfusion ... See more keywords