The prognostic role of 1q21 gain/amplification in newly diagnosed multiple myeloma: The faster, the worse
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DOI: 10.1002/cncr.34641
Abstract: The prognostic value of additional copies of chromosome 1q (1q gain/amplification [amp]) in multiple myeloma (MM) remains controversial. In the meantime, the kinetics of the response to MM therapy has long been an area of… read more here.
Keywords: prognostic role; gain amplification; multiple myeloma;
Outcomes of patients with multiple myeloma harboring chromosome 1q gain/amplification in the era of modern therapy
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DOI: 10.1007/s00277-021-04704-8
Abstract: Chromosome 1q gain/amplification (1q +) has been reported to be associated with inferior outcomes in multiple myeloma (MM) patients. Big therapeutic advances have shifted the treatment landscape by introducing monoclonal antibodies. There is a relative lack… read more here.
Keywords: multiple myeloma; outcomes patients; gain amplification; chromosome gain ... See more keywords
Presentation and outcomes of patients with multiple myeloma harboring gain or amplification of 1q21 and receiving novel agent therapies: results from a single-center study.
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DOI: 10.1080/16078454.2023.2177979
Abstract: OBJECTIVE Gain or amplification 1q21 (1q21+) is one of the most common recurrent cytogenetic abnormalities in multiple myeloma (MM). Our aim was to explore the presentation and outcomes of patients with MM harboring 1q21 + . METHODS… read more here.
Keywords: gain amplification; patients 1q21; amplification 1q21; del 13q ... See more keywords