Gaining Insight into Mitochondrial Genetic Variation and Downstream Pathophysiology: What Can i(PSCs) Do?
Sign Up to like & getrecommendations! Published in 2021 at "Genes"
DOI: 10.3390/genes12111668
Abstract: Mitochondria are specialized organelles involved in energy production that have retained their own genome throughout evolutionary history. The mitochondrial genome (mtDNA) is maternally inherited and requires coordinated regulation with nuclear genes to produce functional enzyme… read more here.
Keywords: heteroplasmic variants; variation; gaining insight; insight mitochondrial ... See more keywords
Tau Isoforms: Gaining Insight into MAPT Alternative Splicing
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315383
Abstract: Tau microtubule-associated proteins, encoded by the MAPT gene, are mainly expressed in neurons participating in axonal transport and synaptic plasticity. Six major isoforms differentially expressed during cell development and differentiation are translated by alternative splicing… read more here.
Keywords: tau; tau isoforms; isoforms gaining; alternative splicing ... See more keywords