Increased Galectin-9 expression, a prognostic biomarker of aGVHD, regulates the immune response through the Galectin-9 induced MDSC pathway after allogeneic hematopoietic stem cell transplantation.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106929
Abstract: Galectin-9 (Gal-9) is a β-galactoside-binding soluble lectin family member that exerts its primary biological functions via specific glycoconjugate interactions. Gal-9 expression is closely related to tumor occurrence, development, metastasis and prognosis. In transplant immunology, a… read more here.
Keywords: gal expression; induced mdsc; transplantation; expression ... See more keywords
Galectin-9 Facilitates Epstein-Barr Virus Latent Infection and Lymphomagenesis in Human B Cells
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DOI: 10.1128/spectrum.04932-22
Abstract: The cross talk between Epstein-Barr virus (EBV) and the host cell transcriptome assumes important roles in the oncogenesis of EBV-associated malignancies. Here, we first observed that endogenous Gal-9 expression was persistently increased along with an… read more here.
Keywords: gal expression; cell; infection; ebv ... See more keywords
Galectin-9 Expression Predicts Favorable Clinical Outcome in Solid Tumors: A Systematic Review and Meta-Analysis
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DOI: 10.3389/fphys.2018.00452
Abstract: Background and Objective: Galectin-9 (Gal-9) is one of the galectin family members which are known as proteins with β-galactoside-binding affinity. Accumulative evidence suggest that Gal-9 plays multifaceted roles in tumor biology. However, the prognostic significance… read more here.
Keywords: gal expression; solid tumors; expression; cancer ... See more keywords
High Galectin-7 and Low Galectin-8 Expression and the Combination of both are Negative Prognosticators for Breast Cancer Patients
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DOI: 10.3390/cancers12040953
Abstract: Galectins are commonly overexpressed in cancer cells and their expression pattern is often associated with the aggressiveness and metastatic phenotype of the tumor. This study investigates the prognostic influence of the expression of galectin-7 (Gal-7)… read more here.
Keywords: gal expression; cytoplasm; galectin; breast cancer ... See more keywords
Overall Survival of Ovarian Cancer Patients Is Determined by Expression of Galectins-8 and -9
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DOI: 10.3390/ijms19010323
Abstract: The evaluation of new prognostic factors that can be targeted in ovarian cancer diagnosis and therapy is of the utmost importance. Galectins are a family of carbohydrate binding proteins with various implications in cancer biology.… read more here.
Keywords: gal expression; overall survival; ovarian cancer; cancer ... See more keywords