Modeling transcriptional activation changes to Gal4 variants via structure-based computational mutagenesis
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DOI: 10.7717/peerj.4844
Abstract: As a DNA binding transcriptional activator, Gal4 promotes the expression of genes responsible for galactose metabolism. The Gal4 protein from Saccharomyces cerevisiae (baker’s yeast) has become a model for studying eukaryotic transcriptional activation in general… read more here.
Keywords: gal4; mutagenesis; gal4 variants; structure ... See more keywords