Characterisation of a Bacterial Galactokinase with High Activity and Broad Substrate Tolerance for Chemoenzymatic Synthesis of 6‐Aminogalactose‐1‐Phosphate and Analogues
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DOI: 10.1002/cbic.201700477
Abstract: Glycosyl phosphates are important intermediates in many metabolic pathways and are substrates for diverse carbohydrate‐active enzymes. Thus, there is a need to develop libraries of structurally similar analogues that can be used as selective chemical… read more here.
Keywords: broad substrate; galactokinase; bacterial galactokinase; aminogalactose phosphate ... See more keywords
Cataract and early nystagmus due to galactokinase deficiency
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DOI: 10.1007/s10545-017-0040-8
Abstract: Galactokinase deficiency (GALK-D, OMIM #230200) is a very rare autosomal recessive inherited disorder in the first step of galactose metabolism presenting as bilateral cataract. The highest incidence is found in Bulgaria and in Bosnia, primarily… read more here.
Keywords: nystagmus; galactokinase; galactokinase deficiency; cataract early ... See more keywords
The Shewanella woodyi galactokinase pool phosphorylates glucose at the 6-position.
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DOI: 10.1016/j.carres.2017.10.018
Abstract: Galactokinases are a class of enzymes which belong to the GHMP (galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase) superfamily and catalyse the phosphorylation of galactose in the first step of the Leloir pathway. Here… read more here.
Keywords: galactokinase; phosphorylates glucose; pool phosphorylates; shewanella woodyi ... See more keywords