Sacha inchi albumin delays skin-aging by alleviating inflammation, oxidative stress and regulating gut microbiota in D-Galactose induced aging mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12555
Abstract: BACKGROUND Sacha inchi albumin exhibits considerable functional activities with notable anti-inflammatory and antioxidation properties, which could further delay skin aging. However, its underlying mechanisms of delaying skin aging have not been elucidated. The aim of… read more here.
Keywords: sacha inchi; galactose induced; inchi albumin; skin aging ... See more keywords
Alpinia oxyphylla Miq extract ameliorates cardiac fibrosis associated with D‐galactose induced aging in rats
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22671
Abstract: Cardiac fibrosis is a common pathophysiological process observed during chronic and stress‐induced acceleration of cardiac aging. Fibrosis is a necessary process during wound healing and tissue repair. However, its deposition in organs would proceed to… read more here.
Keywords: fibrosis; cardiac fibrosis; fibrosis associated; galactose induced ... See more keywords
Astragaloside IV prevents memory impairment in D-galactose-induced aging rats via the AGEs/RAGE/ NF-κB axis.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2021.05.005
Abstract: BACKGROUND We investigated the effects of astragaloside IV (AS-IV) on memory function in aging rats mimicked by D-galactose administration and explored the potential molecular mechanisms. METHODS Twenty-seven male rats were randomly divided into control group… read more here.
Keywords: ages rage; memory impairment; rage axis; galactose induced ... See more keywords
Edaravone attenuates H2O2 or glutamate-induced toxicity in hippocampal neurons and improves AlCl3/D-galactose induced cognitive impairment in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2021.05.005
Abstract: Edaravone (Eda) is a radical scavenger used in clinical trials for the treatment of ischemic stroke and amyotrophic lateral sclerosis. However, how Eda exerts its neuroprotective effects remains to be elucidated. We investigated the neuroprotective… read more here.
Keywords: hippocampal neurons; alcl3 galactose; induced cognitive; cognitive impairment ... See more keywords
Characterization of an i.p. D-galactose-induced cataract model in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmacological and toxicological methods"
DOI: 10.1016/j.vascn.2020.106891
Abstract: Cataracts have been identified as a main cause of global visual impairment and blindness; in addition, diabetic and aging cataracts are the most common types. The aim of this project was to develop a suitable… read more here.
Keywords: characterization galactose; induced cataract; model; cataract model ... See more keywords
Histone acetyltransferase and Polo-like kinase 3 inhibitors prevent rat galactose-induced cataract
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-56414-x
Abstract: Diabetic cataracts can occur at an early age, causing visual impairment or blindness. The detailed molecular mechanisms of diabetic cataract formation remain incompletely understood, and there is no well-documented prophylactic agent. Galactose-fed rats and ex… read more here.
Keywords: formation; induced cataract; galactose induced; histone acetyltransferase ... See more keywords
Antioxidant Efficacy of Protein Hydrolysates from Large Yellow Croaker (Pseudosciaena crocea) in D-galactose-Induced Aging Mice
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Aquatic Food Product Technology"
DOI: 10.1080/10498850.2015.1082525
Abstract: ABSTRACT The antioxidant efficacy of protein hydrolysates prepared from large yellow croaker (Pseudosciaena crocea) by enzymatic hydrolysis using neutral protease was evaluated in D-galactose-induced aging mice. Animals were divided into normal and model control groups,… read more here.
Keywords: galactose induced; yellow croaker; protein hydrolysates; large yellow ... See more keywords
Protocatechuic Aldehyde Alleviates d-Galactose–Induced Cardiomyocyte Senescence by Regulating the TCF3/ATG5 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001394
Abstract: Abstract: Cardiomyocyte senescence is an independent risk factor for cardiovascular diseases. Protocatechuic aldehyde (PCA) is a natural chemical in the Chinese medicinal herb Salvia miltiorrhiza. PCA could protect against oxidative stress and inflammation in the… read more here.
Keywords: inflammation; atg5; galactose induced; cardiomyocyte senescence ... See more keywords
Effects of d‐galactose‐induced ageing on the heart and its potential interventions
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13472
Abstract: Ageing is a strong independent risk factor for disability, morbidity and mortality. Post‐mitotic cells including those in the heart are a particular risk to age‐related deterioration. As the occurrence of heart disease is increasing rapidly… read more here.
Keywords: heart; age related; induced ageing; ageing heart ... See more keywords
D‐galactose‐induced cardiac ageing: A review of model establishment and potential interventions
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17580
Abstract: Cardiovascular disease (CVD) is highly prevalent in an ageing society. The increased incidence and mortality rates of CVD are global issues endangering human health. There is an urgent requirement for understanding the aetiology and pathogenesis… read more here.
Keywords: ageing review; galactose induced; model; induced cardiac ... See more keywords
Ganoderma tsugae prevents cognitive impairment and attenuates oxidative damage in d-galactose-induced aging in the rat brain
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0266331
Abstract: Lingzhi has long been regarded as having life-prolonging effects. Research in recent years has also reported that Lingzhi possesses anti-tumor, anti-inflammatory, immunomodulatory, hepatoprotective, and anti-lipogenic effects. The D-galactose (D-gal, 100 mg/kg/day)-induced aging Long-Evans rats were… read more here.
Keywords: galactose induced; ganoderma tsugae; cognitive impairment; induced aging ... See more keywords