Serum levels of galectin-1, galectin-3, and galectin-9 are associated with large artery atherosclerotic stroke
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DOI: 10.1038/srep40994
Abstract: The aim of this study was to assess the expression patterns of serum galectin-1 (Gal-1), galectin-3 (Gal-3), galectin-9 (Gal-9), and galectin-3 binding protein (Gal-3BP) and their associations with stroke outcome in large artery atherosclerotic (LAA)… read more here.
Keywords: galectin galectin; galectin; serum levels; gal gal ... See more keywords
The therapeutic potential of galectin-1 and galectin-3 in the treatment of neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2020.1750955
Abstract: ABSTRACT Introduction: Neuroinflammation has been proposed as a common factor and one of the main inducers of neuronal degeneration. Galectins are a group of β-galactoside-binding lectins, that play an important role in the immune response,… read more here.
Keywords: galectin galectin; galectin; neurodegenerative diseases; treatment neurodegenerative ... See more keywords
Evaluation of galectins 1 and 3 expression in canine melanoma
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DOI: 10.1590/1678-5150-pvb-6377
Abstract: ABSTRACT: Canine melanoma is a frequently-occuring neoplasm in dogs and presents as malignant and highly metastatic in this context, studies that contribute to the understanding of the tumor microenvironment in melanoma include the role of… read more here.
Keywords: galectin galectin; galectins expression; canine melanoma; melanoma ... See more keywords
Prognostic Significance of Galectin-1 but Not Galectin-3 in Patients With Lung Adenocarcinoma After Radiation Therapy
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DOI: 10.3389/fonc.2022.834749
Abstract: Introduction To investigate the role of tumor galectin-1 and galectin-3 in patients with lung adenocarcinoma after definitive radiation therapy. Methods A total of 41 patients with localized lung adenocarcinoma undergoing thoracic radiation therapy without concurrent… read more here.
Keywords: galectin; galectin galectin; tumor galectin; radiation therapy ... See more keywords
Design, Synthesis, and Anticancer Activity of a Selenium-Containing Galectin-3 and Galectin-9N Inhibitor
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DOI: 10.3390/ijms23052581
Abstract: Galectins are soluble β-D-galactoside-binding proteins whose implication in cancer progression and disease outcome makes them prominent targets for therapeutic intervention. In this frame, the development of small inhibitors that block selectively the activity of galectins… read more here.
Keywords: design synthesis; synthesis anticancer; galectin galectin; activity ... See more keywords