Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models
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DOI: 10.1172/jci97333
Abstract: Uncontrolled secretion of type I IFN, as the result of endosomal TLR (i.e., TLR7 and TLR9) signaling in plasmacytoid DCs (pDCs), and abnormal production of autoantibodies by B cells are critical for systemic lupus erythematosus… read more here.
Keywords: murine; mediated autoimmunity; galectin inhibits; tlr7 mediated ... See more keywords