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   Articles with "gallium iii" as a keyword



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Targeted photodynamic therapy of cancer using a novel gallium (III) tris (ethoxycarbonyl) corrole conjugated‐mAb directed against cancer/testis antigens 83

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recommendations! Published in 2018 at "Cancer Medicine"

DOI: 10.1002/cam4.1601

Abstract: Photodynamic therapy (PDT) is a noninvasive, highly selective approach to the treatment of tumors. However, its therapeutic effect is limited by long‐lasting skin phototoxicity. Therefore, to compromise this shortcoming, it is preferable to deliver photosensitizers… read more here.

Keywords: ct83; photodynamic therapy; gallium iii; testis antigens ... See more keywords
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The Osteosarcoma Stem Cell Activity of a Gallium(III)‐Phenanthroline Complex Appended to Salicylate

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recommendations! Published in 2022 at "Chembiochem"

DOI: 10.1002/cbic.202200532

Abstract: We report the synthesis, characterisation, and anti‐osteosarcoma properties of a gallium(III) complex (1) comprising of two 1,10‐phenanthroline ligands and salicylate, a non‐steroidal anti‐inflammatory drug. The gallium(III) complex 1 displays micromolar potency towards bulk osteosarcoma cells… read more here.

Keywords: iii complex; cell; osteosarcoma; gallium iii ... See more keywords
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Photodynamic Antitumor Activity of 5,15-Bis(perfluorophenyl)-10-(4-carboxyphenyl)corrole and its Gallium(III) and Phosphorus(V) Complexes.

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recommendations! Published in 2022 at "ChemPlusChem"

DOI: 10.1002/cplu.202200188

Abstract: This work reports the preparation and characterization of an A2 B corrole 5,15-bis(perfluorophenyl)-10-(4-carboxyphenyl)corrole and its gallium(III) and phosphorus(V) complexes. Their in-vitro photodynamic anticancer activities against A549, MDA-MB-231, B16, HepG2, and Hela cell lines were also… read more here.

Keywords: carboxyphenyl corrole; corrole gallium; bis perfluorophenyl; gallium iii ... See more keywords
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Hydroxy-corrole and its gallium(III) complex as new photosensitizer for photodynamic therapy against breast carcinoma.

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recommendations! Published in 2020 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2020.112794

Abstract: Three mono-hydroxy corroles 1-3 and their gallium(III) complexes Ga1-3 were synthesized, and their photodynamic antitumour activities towards breast cancer cells were investigated. All corroles showed excellent cytotoxicity against the MDA-MB-231 and 4T1 cell lines upon… read more here.

Keywords: corrole ga3; gallium iii; photodynamic therapy; breast ... See more keywords
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Complex formation reactions of gallium(III) and iron(III/II) with l-proline-thiosemicarbazone hybrids: A comparative study

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recommendations! Published in 2017 at "Inorganica Chimica Acta"

DOI: 10.1016/j.ica.2016.06.044

Abstract: Abstract Three new gallium(III) and iron(III) complexes with l -proline-thiosemicarbazone hybrids, namely [GaCl( l -Pro-FTSC–2H)]·0.7H2O·0.5CH3OH (1·0.7H2O·0.5CH3OH), [GaCl(dm- l -Pro-FTSC–2H)]·0.4H2O (2·0.4H2O) and [FeCl( l -Pro-FTDA–H)]Cl (3) were synthesised and comprehensively characterised by spectroscopic methods (1H, 13C… read more here.

Keywords: iii; iii iron; gallium iii; thiosemicarbazone ... See more keywords
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Water-soluble metalloporphyrinates with excellent photo-induced anticancer activity resulting from high tumor accumulation.

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recommendations! Published in 2017 at "Journal of inorganic biochemistry"

DOI: 10.1016/j.jinorgbio.2017.02.001

Abstract: To develop a water-soluble and tumor-targeted photosensitizer for photodynamic therapy (PDT), a porphyrin framework containing the metal ion gallium(III) was combined with platinum(II)-based groups to produce two new pentacationic metalloporphyrinates, Ga-4cisPtTPyP (5,10,15,20-tetrakis{cis-diammine-chloro-platinum(II)}(4-pyridyl)-porphyrinato gallium(III) hydroxide tetranitrate)… read more here.

Keywords: gallium iii; tumor accumulation; water soluble; tumor ... See more keywords
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Molecular engineering of Ga-ketoiminates: synthesis, structure and evaluation as precursors for the additive-free spin-coated deposition of gallium oxide thin films

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recommendations! Published in 2018 at "New Journal of Chemistry"

DOI: 10.1039/c7nj04334a

Abstract: A series of new homo- and heteroleptic gallium ketoiminate compounds, namely, tris[4-[2-(ethoxyethyl)imino]-2-pentanone] gallium(III) [Ga(eeki)3] [1], tris[4-[3-(methoxypropyl)imino]-2-pentanone] gallium(III), [Ga(mpki)3] [2], tris[4-[3-(methoxyethyl)imino]-2-pentanone] gallium(III), [Ga(meki)3] [3], dichloro[4-[(isopropyl)imino]-2-pentanone] gallium(III) [Ga(ipki)Cl2] [4], bisdimethylamido[4-[(isopropyl)imino]-2-pentanone] gallium(III) [Ga(ipki)(NMe2)2] [5] and chloro-(bis[4-[3-(ethoxypropyl)imino]-2-pentanone]) gallium(III) [Ga(epki)2Cl]… read more here.

Keywords: pentanone gallium; gallium; imino pentanone; gallium iii ... See more keywords

Gallium(III)–2-benzoylpyridine-thiosemicarbazone complexes promote apoptosis through Ca2+ signaling and ROS-mediated mitochondrial pathways

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recommendations! Published in 2018 at "New Journal of Chemistry"

DOI: 10.1039/c8nj00697k

Abstract: Ga(III) compounds are highly promising candidates for antitumor therapy. The level of intracellular reactive oxygen species (ROS) is significantly increased after Ga(III) complex treatment, but these complexes are redox-inactive. To investigate the effects of Ga(III)… read more here.

Keywords: gallium iii; benzoylpyridine thiosemicarbazone; gallium; thiosemicarbazone complexes ... See more keywords
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Antimicrobial Synergism Toward Pseudomonas aeruginosa by Gallium(III) and Inorganic Nitrite

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recommendations! Published in 2020 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2020.02113

Abstract: The ubiquitous involvement of key iron-containing metalloenzymes in metabolism is reflected in the dependence of virtually all bacteria on iron for growth and, thereby, potentially provides multiple biomolecular targets for antimicrobial killing. We hypothesized that… read more here.

Keywords: iron; antimicrobial synergism; pseudomonas aeruginosa; gallium iii ... See more keywords

Gallium (III) Complexes Based on Aminobisphenolate Ligands: Extremely High Active ROP-Initiators from Well-Known and Easily Accessible Compounds

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232415649

Abstract: We report herein the synthesis and full characterizations of the first examples of gallium complexes based on “privileged” aminobisphenolate ligands which are easily available. These complexes turned out to be extremely active in the ring-opening… read more here.

Keywords: rop; complexes based; aminobisphenolate ligands; gallium iii ... See more keywords
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Facile Synthesis of Gallium (III)-Chitosan Complexes as Antibacterial Biomaterial

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recommendations! Published in 2021 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics13101702

Abstract: Even though antibiotic treatment remains one of the most common tools to handle bacterial infections, the excessive antibiotic concentration at the target site may lead to undesired effects. Aiming at the fabrication of antibiotic-free biomaterials… read more here.

Keywords: iii; gallium iii; iii chitosan; synthesis gallium ... See more keywords