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Published in 2022 at "Obesity"
DOI: 10.1002/oby.23427
Abstract: Bariatric surgery increases the risk of postoperative gallstone formation. Many studies have proposed ursodeoxycholic acid (UDCA) as a preventive agent for postoperative gallstone formation. This study aimed to investigate the effect of UDCA on gallstone…
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Keywords:
bariatric surgery;
ursodeoxycholic acid;
gallstone formation;
gallstone ... See more keywords
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Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-021-27758-8
Abstract: Cholesterol gallstone disease is a worldwide common disease. Cholesterol supersaturation in gallbladder bile is the prerequisite for its pathogenesis, while the mechanism is not completely understood. In this study, we find enrichment of gut microbiota…
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Keywords:
bile acid;
gut microbiota;
gallstone;
gallstone formation ... See more keywords
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Published in 2021 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.65485
Abstract: miRNA-223 has been previously reported to play an essential role in hepatic cholesterol homeostasis. However, its role in regulation of biliary cholesterol secretion and gallstone formation remains unknown. Hence, mice with conventional knockout (KO), hepatocyte-specific…
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Keywords:
cholesterol secretion;
mirna 223;
cholesterol;
gallstone formation ... See more keywords